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Serinc5 Gene Detail
Summary
  • Symbol
    Serinc5
  • Name
    serine incorporator 5
  • Synonyms
    A130038L21Rik, AIGP3, TPO1
  • Feature Type
    protein coding gene
  • IDs
    MGI:2444223
    NCBI Gene: 218442
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:92747646-92848455 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 47.75 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2726 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2444223
 protein coding gene Chr13:92747599-92848455 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020819
 protein coding gene Chr13:93930788-94036253 (+)
A/J MGP_AJ_G0020773
 protein coding gene Chr13:90448529-90543666 (+)
AKR/J MGP_AKRJ_G0020746
 protein coding gene Chr13:93182931-93279632 (+)
BALB/cJ MGP_BALBcJ_G0020769
 protein coding gene Chr13:91089007-91186823 (+)
C3H/HeJ MGP_C3HHeJ_G0020563
 protein coding gene Chr13:92900715-92997550 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021206
 protein coding gene Chr13:96780395-96902258 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018773
 protein coding gene Chr13:86373052-86469122 (+)
CAST/EiJ MGP_CASTEiJ_G0020082
 protein coding gene Chr13:92153998-92254236 (+)
CBA/J MGP_CBAJ_G0020522
 protein coding gene Chr13:100635429-100726049 (+)
DBA/2J MGP_DBA2J_G0020647
 protein coding gene Chr13:90208682-90308942 (+)
FVB/NJ MGP_FVBNJ_G0020627
 protein coding gene Chr13:89034114-89127054 (+)
LP/J MGP_LPJ_G0020720
 protein coding gene Chr13:94046252-94150073 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020656
 protein coding gene Chr13:101127243-101233236 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021246
 protein coding gene Chr13:92593924-92687487 (+)
PWK/PhJ MGP_PWKPhJ_G0019834
 protein coding gene Chr13:88950997-89047510 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019658
 protein coding gene Chr13:88851204-88953469 (+)
WSB/EiJ MGP_WSBEiJ_G0020139
 protein coding gene Chr13:93069517-93170118 (+)



Homology
more
  • Human Ortholog
    SERINC5, serine incorporator 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SERINC5, serine incorporator 5
  • Synonyms
    C5orf12, TPO1
  • Links
    NCBI Gene ID: 256987
    neXtProt AC: NX_Q86VE9
    UniProt: Q86VE9

  • Chr Location
    5q14.1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    838
  • Tissues
    39
  • cDNA Data
    129
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 218442 NCBI Gene Model | MGI Sequence Detail 100810 C57BL/6J ±  kb
transcript NM_172588 RefSeq | MGI Sequence Detail 5393 Not Specified  
polypeptide Q8BHJ6 UniProt | EBI | MGI Sequence Detail 461 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 131
    cDNA 130
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 40
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory