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Exoc3l Gene Detail
Summary
  • Symbol
    Exoc3l
  • Name
    exocyst complex component 3-like
  • Synonyms
    C730015A04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:3041195
    NCBI Gene: 277978
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:106016556-106022733 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    185 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3041195
 protein coding gene Chr8:106016555-106024258 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034036
 protein coding gene Chr8:107555143-107561317 (-)
A/J MGP_AJ_G0034017
 protein coding gene Chr8:103267597-103273771 (-)
AKR/J MGP_AKRJ_G0033943
 protein coding gene Chr8:106251551-106257725 (-)
BALB/cJ MGP_BALBcJ_G0034010
 protein coding gene Chr8:103444178-103450352 (-)
C3H/HeJ MGP_C3HHeJ_G0033722
 protein coding gene Chr8:106998881-107005055 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034530
 protein coding gene Chr8:111504369-111510543 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031472
 protein coding gene Chr8:96417072-96423283 (-)
CAST/EiJ MGP_CASTEiJ_G0033048
 protein coding gene Chr8:106498031-106504147 (-)
CBA/J MGP_CBAJ_G0033695
 protein coding gene Chr8:115101635-115107809 (-)
DBA/2J MGP_DBA2J_G0033850
 protein coding gene Chr8:102612671-102618845 (-)
FVB/NJ MGP_FVBNJ_G0033796
 protein coding gene Chr8:101536665-101542839 (-)
LP/J MGP_LPJ_G0033941
 protein coding gene Chr8:107766063-107772237 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033839
 protein coding gene Chr8:118317125-118323299 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034548
 protein coding gene Chr8:106226551-106232725 (-)
PWK/PhJ MGP_PWKPhJ_G0032749
 protein coding gene Chr8:101999157-102005451 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032590
 protein coding gene Chr8:104903320-104909502 (-)
WSB/EiJ MGP_WSBEiJ_G0033164
 protein coding gene Chr8:106879956-106886130 (-)



Homology
more
  • Human Ortholog
    EXOC3L1, exocyst complex component 3 like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EXOC3L1, exocyst complex component 3 like 1
  • Synonyms
    EXOC3L
  • Links
    NCBI Gene ID: 283849
    neXtProt AC: NX_Q86VI1
    UniProt: Q86VI1

  • Chr Location
    16q22.1; chr16:67184379-67190185 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 3 alleles in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null mice are viable and exhibit no apparent phenotype in vascular development, cholesterol homeostasis or insulin secretion.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    12
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    843
  • Tissues
    10
  • cDNA Data
    21
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000043251 Ensembl Gene Model | MGI Sequence Detail 6178 C57BL/6J ±  kb
transcript ENSMUST00000057855 Ensembl | MGI Sequence Detail 2497 Not Applicable  
polypeptide ENSMUSP00000053766 Ensembl | MGI Sequence Detail 739 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000007249 exocyst complex component 3-like protein
    (term hierarchy)
  • InterPro Domains
    IPR010326 Exocyst complex component EXOC3/Sec6
    IPR042532 Exocyst complex component EXOC3/Sec6, C-terminal domain
Molecular
Reagents
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  • All nucleic 22
    Genomic 1
    cDNA 21

    Microarray probesets 1
References
more
  • Summaries
    All 28
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:85162 Hansen J, et al., A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9918-22
  • Latest
    J:345822 Takashima S, et al., Null mutation of exocyst complex component 3-like does not affect vascular development in mice. Exp Anim. 2024 Feb 14;73(1):93-100
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory