About   Help   FAQ
Mtrf1l Gene Detail
Summary
  • Symbol
    Mtrf1l
  • Name
    mitochondrial translational release factor 1-like
  • Synonyms
    9130004K12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918830
    NCBI Gene: 108853
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:5761887-5773910 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 1.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    385 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918830
 protein coding gene Chr10:5760151-5775015 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016987
 protein coding gene Chr10:2901437-2916096 (-)
A/J MGP_AJ_G0016965
 protein coding gene Chr10:2733626-2745728 (-)
AKR/J MGP_AKRJ_G0016930
 protein coding gene Chr10:2759621-2771756 (-)
BALB/cJ MGP_BALBcJ_G0016923
 protein coding gene Chr10:2723531-2735563 (-)
C3H/HeJ MGP_C3HHeJ_G0016748
 protein coding gene Chr10:2867975-2880887 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017386
 protein coding gene Chr10:2988807-3002017 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015092
 protein coding gene Chr10:2482416-2494093 (-)
CAST/EiJ MGP_CASTEiJ_G0016330
 protein coding gene Chr10:2906900-2921266 (-)
CBA/J MGP_CBAJ_G0016720
 protein coding gene Chr10:3075154-3089150 (-)
DBA/2J MGP_DBA2J_G0016828
 protein coding gene Chr10:2716424-2729069 (-)
FVB/NJ MGP_FVBNJ_G0016823
 protein coding gene Chr10:2665863-2678044 (-)
LP/J MGP_LPJ_G0016903
 protein coding gene Chr10:2830584-2842869 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016854
 protein coding gene Chr10:2932526-2945984 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017423
 protein coding gene Chr10:2776592-2788459 (-)
PWK/PhJ MGP_PWKPhJ_G0016116
 protein coding gene Chr10:2730606-2742998 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015898
 protein coding gene Chr10:2988663-3001889 (-)
WSB/EiJ MGP_WSBEiJ_G0016392
 protein coding gene Chr10:2852823-2864552 (-)



Homology
more
  • Human Ortholog
    MTRF1L, mitochondrial translation release factor 1 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MTRF1L, mitochondrial translation release factor 1 like
  • Synonyms
    HMRF1L, MRF1L, mtRF1a
  • Links
    NCBI Gene ID: 54516
    neXtProt AC: NX_Q9UGC7
    UniProt: Q9UGC7

  • Chr Location
    6q25.2; chr6:152987362-153002709 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    14
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019774 Ensembl Gene Model | MGI Sequence Detail 12024 C57BL/6J ±  kb
transcript ENSMUST00000019908 Ensembl | MGI Sequence Detail 2588 Not Applicable  
polypeptide ENSMUSP00000019908 Ensembl | MGI Sequence Detail 373 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010749 peptide chain release factor 1-like, mitochondrial
    (term hierarchy)
  • InterPro Domains
    IPR005139 Peptide chain release factor
    IPR000352 Peptide chain release factor class I
    IPR045853 Peptide chain release factor class I superfamily
    IPR050057 Prokaryotic/Mitochondrial Release Factor
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 2
References
more
  • Summaries
    All 27
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory