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Fsbp Gene Detail
Summary
  • Symbol
    Fsbp
  • Name
    fibrinogen silencer binding protein
  • Feature Type
    protein coding gene
  • IDs
    MGI:5301008
    NCBI Gene: 100503583
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:11579665-11587591 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 5.11 cM
Strain
Comparison
more
  • SNPs within 2kb
    245 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5301008
 protein coding gene Chr4:11579662-11587802 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028055
 protein coding gene Chr4:8253322-8262061 (+)
A/J MGP_AJ_G0028012
 protein coding gene Chr4:8119833-8127756 (+)
AKR/J MGP_AKRJ_G0027978
 protein coding gene Chr4:8205822-8213743 (+)
BALB/cJ MGP_BALBcJ_G0028024
 protein coding gene Chr4:8045710-8053636 (+)
C3H/HeJ MGP_C3HHeJ_G0027754
 protein coding gene Chr4:8382016-8389957 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028467
 protein coding gene Chr4:8663020-8671031 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025811
 protein coding gene Chr4:7639440-7647648 (+)
CAST/EiJ MGP_CASTEiJ_G0027208
 protein coding gene Chr4:8194754-8204347 (+)
CBA/J MGP_CBAJ_G0027729
 protein coding gene Chr4:8907006-8914933 (+)
DBA/2J MGP_DBA2J_G0027870
 protein coding gene Chr4:7989472-7997241 (+)
FVB/NJ MGP_FVBNJ_G0027836
 protein coding gene Chr4:7819619-7827765 (+)
LP/J MGP_LPJ_G0027980
 protein coding gene Chr4:8332129-8341615 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027869
 protein coding gene Chr4:9083361-9099180 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028526
 protein coding gene Chr4:8213730-8222414 (+)
PWK/PhJ MGP_PWKPhJ_G0026929
 protein coding gene Chr4:8004232-8012759 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026759
 protein coding gene Chr4:8123676-8131707 (+)
WSB/EiJ MGP_WSBEiJ_G0027287
 protein coding gene Chr4:8276125-8282966 (+)



Homology
more
  • Human Ortholog
    FSBP, fibrinogen silencer binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FSBP, fibrinogen silencer binding protein
  • Links
    NCBI Gene ID: 100861412
    neXtProt AC: NX_O95073
    UniProt: O95073

  • Chr Location
    8q22.1; chr8:94378377-94436952 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000094595 Ensembl Gene Model | MGI Sequence Detail 7927 C57BL/6J ±  kb
transcript ENSMUST00000180239 Ensembl | MGI Sequence Detail 4358 Not Applicable  
polypeptide ENSMUSP00000137082 Ensembl | MGI Sequence Detail 299 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 4
    cDNA 4
References
more
  • Summaries
    All 17
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory