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Gpc2 Gene Detail
Summary
  • Symbol
    Gpc2
  • Name
    glypican 2 cerebroglycan
  • Synonyms
    2410016G05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919201
    NCBI Gene: 71951
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:138271917-138278267 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 77.00 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    191 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919201
 protein coding gene Chr5:138271917-138278288 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030267
 protein coding gene Chr5:143123442-143129792 (-)
A/J MGP_AJ_G0030235
 protein coding gene Chr5:137002737-137009087 (-)
AKR/J MGP_AKRJ_G0030167
 protein coding gene Chr5:141374796-141381146 (-)
BALB/cJ MGP_BALBcJ_G0030249
 protein coding gene Chr5:138337129-138343479 (-)
C3H/HeJ MGP_C3HHeJ_G0029962
 protein coding gene Chr5:142098385-142104735 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030696
 protein coding gene Chr5:148421526-148427876 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027913
 protein coding gene Chr5:131021860-131028127 (-)
CAST/EiJ MGP_CASTEiJ_G0029368
 protein coding gene Chr5:141434248-141440600 (-)
CBA/J MGP_CBAJ_G0029933
 protein coding gene Chr5:154473428-154479778 (-)
DBA/2J MGP_DBA2J_G0030081
 protein coding gene Chr5:136896376-136902726 (-)
FVB/NJ MGP_FVBNJ_G0030039
 protein coding gene Chr5:135998548-136004898 (-)
LP/J MGP_LPJ_G0030170
 protein coding gene Chr5:143670482-143676832 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030070
 protein coding gene Chr5:157225567-157231917 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030737
 protein coding gene Chr5:141179959-141186313 (-)
PWK/PhJ MGP_PWKPhJ_G0029082
 protein coding gene Chr5:135862745-135869097 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028917
 protein coding gene Chr5:138784117-138790457 (-)
WSB/EiJ MGP_WSBEiJ_G0029443
 protein coding gene Chr5:141868071-141874441 (-)



Homology
more
  • Human Ortholog
    GPC2, glypican 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPC2, glypican 2
  • Links
    NCBI Gene ID: 221914
    neXtProt AC: NX_Q8N158
    UniProt: Q8N158

  • Chr Location
    7q22.1; chr7:100169606-100177381 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 3 alleles in 3 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are phenotypically normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    835
  • Tissues
    43
  • cDNA Data
    20
  • Literature Summary
    15
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000029510 Ensembl Gene Model | MGI Sequence Detail 6351 C57BL/6J ±  kb
    transcript ENSMUST00000161827 Ensembl | MGI Sequence Detail 2586 Not Applicable  
    polypeptide ENSMUSP00000124459 Ensembl | MGI Sequence Detail 579 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 23
      cDNA 20
      Primer pair 3

      Microarray probesets 3
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 15
      Gene Ontology 8
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/22/2024
    MGI 6.24     		The Jackson Laboratory