About   Help   FAQ
Adamtsl1 Gene Detail
Summary
  • Symbol
    Adamtsl1
  • Name
    ADAMTS-like 1
  • Synonyms
    5930437A14Rik, 6720426B09Rik, punctin-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924989
    NCBI Gene: 77739
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:85432409-86346622 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 40.32 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    25347 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924989
 protein coding gene Chr4:85432242-86346627 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028409
 protein coding gene Chr4:85797809-86188395 (+)
A/J MGP_AJ_G0028370
 protein coding gene Chr4:82774777-83153707 (+)
AKR/J MGP_AKRJ_G0028319
 protein coding gene Chr4:84901204-85282983 (+)
BALB/cJ MGP_BALBcJ_G0028390
 protein coding gene Chr4:82989628-83379136 (+)
C3H/HeJ MGP_C3HHeJ_G0028105
 protein coding gene Chr4:85548930-85939457 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028829
 protein coding gene Chr4:89074712-89459229 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026129
 protein coding gene Chr4:78650933-79014672 (+)
CAST/EiJ MGP_CASTEiJ_G0027546
 protein coding gene Chr4:83451666-83834255 (+)
CBA/J MGP_CBAJ_G0028074
 protein coding gene Chr4:91821960-92236828 (+)
DBA/2J MGP_DBA2J_G0028223
 protein coding gene Chr4:82558265-82934057 (+)
FVB/NJ MGP_FVBNJ_G0028189
 protein coding gene Chr4:81547270-81924191 (+)
LP/J MGP_LPJ_G0028323
 protein coding gene Chr4:86125541-86522729 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028218
 protein coding gene Chr4:96902459-97298131 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028866
 protein coding gene Chr4:84981551-85361368 (+)
PWK/PhJ MGP_PWKPhJ_G0027269
 protein coding gene Chr4:80909390-81278040 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027094
 protein coding gene Chr4:82531574-82916270 (+)
WSB/EiJ MGP_WSBEiJ_G0027622
 protein coding gene Chr4:85170034-85547608 (+)



Homology
more
  • Human Ortholog
    ADAMTSL1, ADAMTS like 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ADAMTSL1, ADAMTS like 1
  • Synonyms
    ADAMTSL-1, ADAMTSR1, C9orf94, PUNCTIN
  • Links
    NCBI Gene ID: 92949
    neXtProt AC: NX_Q8N6G6
    UniProt: Q8N6G6

  • Chr Location
    9p22.2-p22.1; chr9:17906563-18910950 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    23
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000066113 Ensembl Gene Model | MGI Sequence Detail 914214 C57BL/6J ±  kb
transcript ENSMUST00000107178 Ensembl | MGI Sequence Detail 7839 Not Applicable  
polypeptide ENSMUSP00000102796 Ensembl | MGI Sequence Detail 1753 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 23
    Primer pair 1

    Microarray probesets 8
Other
Accession IDs
less
MGI:2682933
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:265607 Naba A, et al., Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Sci Rep. 2017 Jan 10;7:40495
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory