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Tcaf1 Gene Detail
Summary
  • Symbol
    Tcaf1
  • Name
    TRPM8 channel-associated factor 1
  • Synonyms
    2810407D09Rik, 3321401G04Rik, A230020K05Rik, Fam115a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914665
    NCBI Gene: 77574
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:42644936-42687022 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 20.84 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1368 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914665
 protein coding gene Chr6:42644933-42687065 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030659
 protein coding gene Chr6:41196940-41242574 (-)
A/J MGP_AJ_G0030632
 protein coding gene Chr6:39402458-39444117 (-)
AKR/J MGP_AKRJ_G0030557
 protein coding gene Chr6:40658344-40701313 (-)
BALB/cJ MGP_BALBcJ_G0030642
 protein coding gene Chr6:39654491-39696177 (-)
C3H/HeJ MGP_C3HHeJ_G0030355
 protein coding gene Chr6:40700970-40742920 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031096
 protein coding gene Chr6:42219678-42261380 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028303
 protein coding gene Chr6:37265552-37310190 (-)
CAST/EiJ MGP_CASTEiJ_G0029759
 protein coding gene Chr6:40546511-40597575 (-)
CBA/J MGP_CBAJ_G0030330
 protein coding gene Chr6:43929509-43970953 (-)
DBA/2J MGP_DBA2J_G0030475
 protein coding gene Chr6:39244780-39286342 (-)
FVB/NJ MGP_FVBNJ_G0030431
 protein coding gene Chr6:38994352-39037187 (-)
LP/J MGP_LPJ_G0030563
 protein coding gene Chr6:41171055-41214543 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030465
 protein coding gene Chr6:46207446-46256132 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031126
 protein coding gene Chr6:40632569-40675499 (-)
PWK/PhJ MGP_PWKPhJ_G0029471
 protein coding gene Chr6:38811461-38854150 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029307
 protein coding gene Chr6:40178428-40221577 (-)
WSB/EiJ MGP_WSBEiJ_G0029835
 protein coding gene Chr6:40636199-40681274 (-)



Homology
more
  • Human Ortholog
    TCAF1, TRPM8 channel associated factor 1
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TCAF1, TRPM8 channel associated factor 1
  • Synonyms
    FAM115A, GATD9A
  • Links
    NCBI Gene ID: 9747
    neXtProt AC: NX_Q9Y4C2
    UniProt: Q9Y4C2

  • Chr Location
    7q35; chr7:143851375-143902198 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    775
  • Tissues
    12
  • cDNA Data
    19
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036667 Ensembl Gene Model | MGI Sequence Detail 42087 C57BL/6J ±  kb
transcript ENSMUST00000121083 Ensembl | MGI Sequence Detail 3342 Not Applicable  
polypeptide ENSMUSP00000114036 Ensembl | MGI Sequence Detail 922 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000030760 TRPM8 channel-associated factor 1
    (term hierarchy)
  • InterPro Domains
    IPR029062 Class I glutamine amidotransferase-like
    IPR035423 M60-like domain, N-terminal
    IPR031161 Peptidase family M60 domain
    IPR042279 Peptidase M60, enhancin-like domain 3
    IPR051244 TRPM8 Channel-Associated Factors
  • GlyGen
    Q8BNE1 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 8
Other
Accession IDs
less
MGI:1916483, MGI:1924824, MGI:2141498
References
more
  • Summaries
    All 28
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory