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Tmem177 Gene Detail
Summary
  • Symbol
    Tmem177
  • Name
    transmembrane protein 177
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913593
    NCBI Gene: 66343
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:119835620-119840913 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 52.53 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    196 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913593
 protein coding gene Chr1:119835620-119840938 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016399
 protein coding gene Chr1:122682270-122687587 (-)
A/J MGP_AJ_G0016382
 protein coding gene Chr1:118284610-118289927 (-)
AKR/J MGP_AKRJ_G0016347
 protein coding gene Chr1:121771808-121777125 (-)
BALB/cJ MGP_BALBcJ_G0016342
 protein coding gene Chr1:118545385-118550702 (-)
C3H/HeJ MGP_C3HHeJ_G0016168
 protein coding gene Chr1:121935244-121940561 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016803
 protein coding gene Chr1:127357265-127362583 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014516
 protein coding gene Chr1:111936028-111941352 (-)
CAST/EiJ MGP_CASTEiJ_G0015749
 protein coding gene Chr1:120716946-120722254 (-)
CBA/J MGP_CBAJ_G0016141
 protein coding gene Chr1:131764703-131770020 (-)
DBA/2J MGP_DBA2J_G0016247
 protein coding gene Chr1:117307415-117312732 (-)
FVB/NJ MGP_FVBNJ_G0016246
 protein coding gene Chr1:116057947-116063264 (-)
LP/J MGP_LPJ_G0016318
 protein coding gene Chr1:124024785-124030102 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016271
 protein coding gene Chr1:137516607-137521924 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016839
 protein coding gene Chr1:121481149-121486465 (-)
PWK/PhJ MGP_PWKPhJ_G0015535
 protein coding gene Chr1:116283168-116288202 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015323
 protein coding gene Chr1:120374507-120379832 (-)
WSB/EiJ MGP_WSBEiJ_G0015811
 protein coding gene Chr1:121365753-121371072 (-)



Homology
more
  • Human Ortholog
    TMEM177, transmembrane protein 177
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM177, transmembrane protein 177
  • Links
    NCBI Gene ID: 80775
    neXtProt AC: NX_Q53S58
    UniProt: Q53S58

  • Chr Location
    2q14.2; chr2:119679167-119723618 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    4
  • cDNA Data
    25
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66343 NCBI Gene Model | MGI Sequence Detail 5294 C57BL/6J ±  kb
transcript NM_175106 RefSeq | MGI Sequence Detail 3316 C57BL/6  
polypeptide Q8BPE4 UniProt | EBI | MGI Sequence Detail 311 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 4
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory