Slc26a9 MGI Mouse Gene Detail - MGI:2444594 - solute carrier family 26, member 9

Symbol

Slc26a9
Name

solute carrier family 26, member 9
Synonyms

anion transporter/exchanger-9, E030002L01Rik

Feature Type

protein coding gene
IDs

MGI:2444594
NCBI Gene: 320718
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr1:131671760-131699242 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 57.18 cM
Mapping Data

1 experiment

SNPs within 2kb

775 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_2444594	protein coding gene	Chr1:131671760-131699242 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0016458	protein coding gene	Chr1:135172753-135199993 (+)
A/J	MGP_AJ_G0016441	protein coding gene	Chr1:130183328-130210730 (+)
AKR/J	MGP_AKRJ_G0016406	protein coding gene	Chr1:134003924-134031165 (+)
BALB/cJ	MGP_BALBcJ_G0016401	protein coding gene	Chr1:130501653-130529398 (+)
C3H/HeJ	MGP_C3HHeJ_G0016227	protein coding gene	Chr1:134149422-134176883 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016862	protein coding gene	Chr1:140204909-140232374 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014576	protein coding gene	Chr1:123309375-123337516 (+)
CAST/EiJ	MGP_CASTEiJ_G0015807	protein coding gene	Chr1:133142840-133170335 (+)
CBA/J	MGP_CBAJ_G0016199	protein coding gene	Chr1:144992224-145019803 (+)
DBA/2J	MGP_DBA2J_G0016306	protein coding gene	Chr1:129142970-129170323 (+)
FVB/NJ	MGP_FVBNJ_G0016305	protein coding gene	Chr1:127770127-127797550 (+)
LP/J	MGP_LPJ_G0016377	protein coding gene	Chr1:136496428-136523884 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016330	protein coding gene	Chr1:150770054-150797542 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016898	protein coding gene	Chr1:133765779-133793142 (+)
PWK/PhJ	MGP_PWKPhJ_G0015593	protein coding gene	Chr1:128100032-128127669 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0015380	protein coding gene	Chr1:132704604-132734279 (+)
WSB/EiJ	MGP_WSBEiJ_G0015869	protein coding gene	Chr1:133748570-133775913 (+)

Human Ortholog

SLC26A9, solute carrier family 26 member 9

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLC26A9, solute carrier family 26 member 9
Links

HGNC:14469

NCBI Gene ID: 115019

neXtProt AC: NX_Q7LBE3

UniProt: Q7LBE3
Chr Location

1q32.1; chr1:205913048-205943460 (-) GRCh38

MGI Vertebrate Homology

Slc26a9 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SLC26A9
Gene Tree

Slc26a9

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Phenotype Summary

18 phenotypes from 2 alleles in 2 genetic backgrounds
1 images
18 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

20
Chemically induced (other)

2
Endonuclease-mediated

2
Gene trapped

14
Radiation induced

1
Targeted

1
Genomic Mutations

3 involving Slc26a9
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

76 strains or lines available
Comparison Matrix

Gene Expression + Phenotype
Recombinase Activity

Comparison Matrix Gene Expression + Recombinase Activity

Mice homozygous for a null allele exhibit reduced gastric secretory membranes and loss of gastric acid secretion.

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All GO Annotations

34
GO References

6

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

852
Tissues

111
cDNA Data

9
Literature Summary

7

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase slc26a9

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All Sequences

43
RefSeq

9
UniProt

4
CCDS

CCDS15273.1

Ensembl

ENSMUSG00000042268 (Evidence)
NCBI Gene

320718

			Length	Strain/Species	Flank
genomic	320718	NCBI Gene Model \| MGI Sequence Detail	27483	C57BL/6J	± kb
transcript	NM_177243	RefSeq \| MGI Sequence Detail	3640	C57BL/6
polypeptide	Q8BU91	UniProt \| EBI \| MGI Sequence Detail	790	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000015044 solute carrier family 26 member 9

(term hierarchy)
PDB

6RTC, 6RTF
InterPro Domains

IPR001902 SLC26A/SulP transporter

IPR011547 SLC26A/SulP transporter domain

IPR002645 STAS domain

IPR036513 STAS domain superfamily

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All nucleic 13

cDNA 9

Primer pair 3

Other 1

Microarray probesets 1

Summaries

All 43

Developmental Gene Expression 7

Gene Ontology 6

Phenotypes 18
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:353597 Powers KG, et al., Deletion of the Ebf1, a mouse deafness gene, causes a dramatic increase in hair cells and support cells of the organ of Corti. Development. 2024 Aug 15;151(16)

TSS for Slc26a9:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr8660	Chr1:131671749-131671767 (+)	-2 bp
Tssr8661	Chr1:131671916-131671933 (+)	165 bp
Tssr8662	Chr1:131678119-131678124 (+)	6,362 bp
Tssr8663	Chr1:131678223-131678232 (+)	6,468 bp
Tssr8664	Chr1:131678244-131678257 (+)	6,491 bp
Tssr8665	Chr1:131688057-131688065 (+)	16,301 bp
Tssr8666	Chr1:131689295-131689301 (+)	17,538 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24