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Mblac1 Gene Detail
Summary
  • Symbol
    Mblac1
  • Name
    metallo-beta-lactamase domain containing 1
  • Synonyms
    MGC:49416
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679717
    NCBI Gene: 330216
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:138192576-138193883 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 76.98 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    136 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679717
 protein coding gene Chr5:138192576-138193883 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030261
 protein coding gene Chr5:142990433-142991740 (+)
A/J MGP_AJ_G0030229
 protein coding gene Chr5:136808867-136810174 (+)
AKR/J MGP_AKRJ_G0030161
 protein coding gene Chr5:141261328-141262635 (+)
BALB/cJ MGP_BALBcJ_G0030243
 protein coding gene Chr5:138168469-138169776 (+)
C3H/HeJ MGP_C3HHeJ_G0029956
 protein coding gene Chr5:141890347-141891654 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030690
 protein coding gene Chr5:148343671-148344978 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027908
 protein coding gene Chr5:130942836-130944142 (+)
CAST/EiJ MGP_CASTEiJ_G0029362
 protein coding gene Chr5:141270988-141272297 (+)
CBA/J MGP_CBAJ_G0029927
 protein coding gene Chr5:154220827-154222134 (+)
DBA/2J MGP_DBA2J_G0030075
 protein coding gene Chr5:136708293-136709600 (+)
FVB/NJ MGP_FVBNJ_G0030033
 protein coding gene Chr5:135872970-135874277 (+)
LP/J MGP_LPJ_G0030164
 protein coding gene Chr5:143530420-143531727 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030064
 protein coding gene Chr5:157046134-157047441 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030731
 protein coding gene Chr5:141096870-141098177 (+)
PWK/PhJ MGP_PWKPhJ_G0029076
 protein coding gene Chr5:135767161-135768468 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028912
 protein coding gene Chr5:138657699-138659006 (+)
WSB/EiJ MGP_WSBEiJ_G0029437
 protein coding gene Chr5:141786312-141787620 (+)



Homology
more
  • Human Ortholog
    MBLAC1, metallo-beta-lactamase domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MBLAC1, metallo-beta-lactamase domain containing 1
  • Links
    NCBI Gene ID: 255374
    neXtProt AC: NX_A4D2B0
    UniProt: A4D2B0

  • Chr Location
    7q22.1; chr7:100126785-100128495 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 330216 NCBI Gene Model | MGI Sequence Detail 1308 C57BL/6J ±  kb
transcript NM_177878 RefSeq | MGI Sequence Detail 1308 C57BL/6  
polypeptide Q8BWY4 UniProt | EBI | MGI Sequence Detail 260 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:344444 Ceyhan B, et al., Optical Imaging Reveals Liver Metabolic Perturbations in Mblac1 Knockout Mice. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul;2023:1-4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory