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Lrtm1 Gene Detail
Summary
  • Symbol
    Lrtm1
  • Name
    leucine-rich repeats and transmembrane domains 1
  • Synonyms
    A930016D02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442106
    NCBI Gene: 319476
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:28740165-28755599 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 16.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    498 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442106
 protein coding gene Chr14:28740165-28755602 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021097
 protein coding gene Chr14:22086711-22102887 (+)
A/J MGP_AJ_G0021045
 protein coding gene Chr14:21257742-21273904 (+)
AKR/J MGP_AKRJ_G0021022
 protein coding gene Chr14:22321784-22337212 (+)
BALB/cJ MGP_BALBcJ_G0021049
 protein coding gene Chr14:21343724-21359142 (+)
C3H/HeJ MGP_C3HHeJ_G0020832
 protein coding gene Chr14:22180239-22195660 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021481
 protein coding gene Chr14:22981098-22996533 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019044
 protein coding gene Chr14:21343454-21358902 (+)
CAST/EiJ MGP_CASTEiJ_G0020357
 protein coding gene Chr14:21879540-21895009 (+)
CBA/J MGP_CBAJ_G0020799
 protein coding gene Chr14:23870579-23886006 (+)
DBA/2J MGP_DBA2J_G0020921
 protein coding gene Chr14:21302995-21318413 (+)
FVB/NJ MGP_FVBNJ_G0020905
 protein coding gene Chr14:21254322-21269746 (+)
LP/J MGP_LPJ_G0020990
 protein coding gene Chr14:22412701-22428116 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020931
 protein coding gene Chr14:23198335-23213853 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021514
 protein coding gene Chr14:22090722-22106143 (+)
PWK/PhJ MGP_PWKPhJ_G0020105
 protein coding gene Chr14:20718957-20734498 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019929
 protein coding gene Chr14:21619127-21634658 (+)
WSB/EiJ MGP_WSBEiJ_G0020412
 protein coding gene Chr14:22144342-22159763 (+)



Homology
more
  • Human Ortholog
    LRTM1, leucine rich repeats and transmembrane domains 1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRTM1, leucine rich repeats and transmembrane domains 1
  • Synonyms
    HT017
  • Links
    NCBI Gene ID: 57408
    neXtProt AC: NX_Q9HBL6
    UniProt: Q9HBL6

  • Chr Location
    3p14.3; chr3:54918231-54967102 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    23
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 319476 NCBI Gene Model | MGI Sequence Detail 15435 C57BL/6J ±  kb
transcript NM_176920 RefSeq | MGI Sequence Detail 7318 C57BL/6  
polypeptide Q8BXQ3 UniProt | EBI | MGI Sequence Detail 356 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000029611 leucine-rich repeat and transmembrane domain-containing protein 1
    (term hierarchy)
  • InterPro Domains
    IPR000483 Cysteine-rich flanking region, C-terminal
    IPR001611 Leucine-rich repeat
    IPR050541 Leucine-rich repeat and transmembrane domain-containing protein
    IPR032675 Leucine-rich repeat domain superfamily
    IPR000372 Leucine-rich repeat N-terminal domain
    IPR003591 Leucine-rich repeat, typical subtype
  • GlyGen
    Q8BXQ3 3 sites
Molecular
Reagents
less
  • All nucleic 24
    cDNA 23
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 25
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 3
  • Earliest
    J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
  • Latest
    J:236231 Nishihara H, et al., Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate. PLoS Genet. 2016 Oct;12(10):e1006380
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory