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Phactr3 Gene Detail
Summary
  • Symbol
    Phactr3
  • Name
    phosphatase and actin regulator 3
  • Synonyms
    1500003N10Rik, 4930415A02Rik, scapinin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921439
    NCBI Gene: 74189
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:177760768-177980285 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 99.67 cM, cytoband H4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6671 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921439
 protein coding gene Chr2:177760768-177980285 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026975
 protein coding gene Chr2:184533006-184763103 (+)
A/J MGP_AJ_G0026941
 protein coding gene Chr2:176933065-177154816 (+)
AKR/J MGP_AKRJ_G0026911
 protein coding gene Chr2:182226815-182453425 (+)
BALB/cJ MGP_BALBcJ_G0026950
 protein coding gene Chr2:177409373-177628134 (+)
C3H/HeJ MGP_C3HHeJ_G0026691
 protein coding gene Chr2:182603930-182834456 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027396
 protein coding gene Chr2:189888904-190124122 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024765
 protein coding gene Chr2:167618208-167842680 (+)
CAST/EiJ MGP_CASTEiJ_G0026150
 protein coding gene Chr2:180813946-181053034 (+)
CBA/J MGP_CBAJ_G0026668
 protein coding gene Chr2:196773542-197003004 (+)
DBA/2J MGP_DBA2J_G0026806
 protein coding gene Chr2:176051844-176279379 (+)
FVB/NJ MGP_FVBNJ_G0026772
 protein coding gene Chr2:174640091-174867057 (+)
LP/J MGP_LPJ_G0026907
 protein coding gene Chr2:184490011-184719398 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026791
 protein coding gene Chr2:199463514-199694085 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027455
 protein coding gene Chr2:182194237-182425806 (+)
PWK/PhJ MGP_PWKPhJ_G0025886
 protein coding gene Chr2:173516264-173770028 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025686
 protein coding gene Chr2:178655318-178907640 (+)
WSB/EiJ MGP_WSBEiJ_G0026222
 protein coding gene Chr2:183181608-183411697 (+)



Homology
more
  • Human Ortholog
    PHACTR3, phosphatase and actin regulator 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PHACTR3, phosphatase and actin regulator 3
  • Synonyms
    C20orf101, H17739, PPP1R123, SCAPIN1, SCAPININ
  • Links
    NCBI Gene ID: 116154
    neXtProt AC: NX_Q96KR7
    UniProt: Q96KR7

  • Chr Location
    20q13.32-q13.33
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    44
  • cDNA Data
    13
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74189 NCBI Gene Model | MGI Sequence Detail 219518 C57BL/6J ±  kb
transcript NM_028806 RefSeq | MGI Sequence Detail 5100 C57BL/6  
polypeptide Q8BYK5 UniProt | EBI | MGI Sequence Detail 558 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 13
    Primer pair 1
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1921108
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory