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Chpt1 Gene Detail
Summary
  • Symbol
    Chpt1
  • Name
    choline phosphotransferase 1
  • Synonyms
    MGC:28885
  • Feature Type
    protein coding gene
  • IDs
    MGI:2384841
    NCBI Gene: 212862
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:88305376-88339855 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 43.93 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    939 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2384841
 protein coding gene Chr10:88288607-88339935 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017627
 protein coding gene Chr10:89536967-89595897 (-)
A/J MGP_AJ_G0017606
 protein coding gene Chr10:86512802-86565049 (-)
AKR/J MGP_AKRJ_G0017564
 protein coding gene Chr10:88974863-89029044 (-)
BALB/cJ MGP_BALBcJ_G0017569
 protein coding gene Chr10:86795261-86848414 (-)
C3H/HeJ MGP_C3HHeJ_G0017392
 protein coding gene Chr10:88950469-89002900 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018026
 protein coding gene Chr10:92551508-92607026 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015708
 protein coding gene Chr10:82286015-82334574 (-)
CAST/EiJ MGP_CASTEiJ_G0016957
 protein coding gene Chr10:88868289-88929836 (-)
CBA/J MGP_CBAJ_G0017361
 protein coding gene Chr10:96379957-96434812 (-)
DBA/2J MGP_DBA2J_G0017467
 protein coding gene Chr10:85633998-85684520 (-)
FVB/NJ MGP_FVBNJ_G0017459
 protein coding gene Chr10:84857998-84908348 (-)
LP/J MGP_LPJ_G0017541
 protein coding gene Chr10:90208329-90268254 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017490
 protein coding gene Chr10:97875488-97937307 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018063
 protein coding gene Chr10:88810477-88862961 (-)
PWK/PhJ MGP_PWKPhJ_G0016738
 protein coding gene Chr10:85655579-85708983 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016527
 protein coding gene Chr10:87568841-87603332 (-)
WSB/EiJ MGP_WSBEiJ_G0017016
 protein coding gene Chr10:88790490-88851323 (-)



Homology
more
  • Human Ortholog
    CHPT1, choline phosphotransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHPT1, choline phosphotransferase 1
  • Synonyms
    CPT, CPT1
  • Links
    NCBI Gene ID: 56994
    neXtProt AC: NX_Q8WUD6
    UniProt: Q8WUD6

  • Chr Location
    12q23.2; chr12:101696947-101744140 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    893
  • Tissues
    151
  • cDNA Data
    11
  • Literature Summary
    7
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 212862 NCBI Gene Model | MGI Sequence Detail 34480 C57BL/6J ±  kb
transcript NM_144807 RefSeq | MGI Sequence Detail 3239 C57BL/6  
polypeptide Q8C025 UniProt | EBI | MGI Sequence Detail 398 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000005449 cholinephosphotransferase 1
    (term hierarchy)
  • EC
    2.7.8.2
  • InterPro Domains
    IPR000462 CDP-alcohol phosphatidyltransferase
    IPR048254 CDP-alcohol phosphatidyltransferase, conserved site
    IPR043130 CDP-alcohol phosphatidyltransferase, transmembrane domain
    IPR014472 Choline/ethanolamine phosphotransferase
  • GlyGen
    Q8C025 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
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  • All nucleic 16
    cDNA 12
    Primer pair 4

    Microarray probesets 4
References
more
  • Summaries
    All 46
    Developmental Gene Expression 7
    Gene Ontology 7
    Phenotypes 17
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory