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Exog Gene Detail
Summary
  • Symbol
    Exog
  • Name
    exo/endonuclease G
  • Synonyms
    Endogl1, ENDOGL2, ENGL-a, ENGL-B
  • Feature Type
    protein coding gene
  • IDs
    MGI:2143333
    NCBI Gene: 208194
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:119274026-119294584 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 71.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    573 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2143333
 protein coding gene Chr9:119274009-119294584 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035420
 protein coding gene Chr9:122221119-122246452 (+)
A/J MGP_AJ_G0035401
 protein coding gene Chr9:117667149-117687513 (+)
AKR/J MGP_AKRJ_G0035334
 protein coding gene Chr9:120739271-120762254 (+)
BALB/cJ MGP_BALBcJ_G0035397
 protein coding gene Chr9:117545772-117567066 (+)
C3H/HeJ MGP_C3HHeJ_G0035105
 protein coding gene Chr9:121201097-121225114 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035920
 protein coding gene Chr9:125551758-125578388 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032802
 protein coding gene Chr9:114866861-114888605 (+)
CAST/EiJ MGP_CASTEiJ_G0034408
 protein coding gene Chr9:121189915-121214172 (+)
CBA/J MGP_CBAJ_G0035072
 protein coding gene Chr9:130265683-130295344 (+)
DBA/2J MGP_DBA2J_G0035231
 protein coding gene Chr9:117109326-117131259 (+)
FVB/NJ MGP_FVBNJ_G0035178
 protein coding gene Chr9:115968762-115990054 (+)
LP/J MGP_LPJ_G0035310
 protein coding gene Chr9:122562309-122581992 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035219
 protein coding gene Chr9:131232034-131257911 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035939
 protein coding gene Chr9:121122438-121145367 (+)
PWK/PhJ MGP_PWKPhJ_G0034114
 protein coding gene Chr9:117541075-117562762 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033950
 protein coding gene Chr9:121226706-121248183 (+)
WSB/EiJ MGP_WSBEiJ_G0034529
 protein coding gene Chr9:121006904-121029093 (+)



Homology
more
  • Human Ortholog
    EXOG, exo/endonuclease G
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    EXOG, exo/endonuclease G
  • Synonyms
    ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGLA, ENGL-b, ENGLB
  • Links
    NCBI Gene ID: 9941
    neXtProt AC: NX_Q9Y2C4
    UniProt: Q9Y2C4

  • Chr Location
    3p22.2; chr3:38496127-38542161 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    52
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 208194 NCBI Gene Model | MGI Sequence Detail 20559 C57BL/6J ±  kb
transcript NM_001410591 RefSeq | MGI Sequence Detail 3965 C57BL/6  
polypeptide Q8C163 UniProt | EBI | MGI Sequence Detail 368 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 52

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 4
  • Earliest
    J:91812 Stryke D, et al., BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Nucleic Acids Res. 2003 Jan 1;31(1):278-81
  • Latest
    J:281596 Man JCK, et al., An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo. Nat Commun. 2019 Oct 30;10(1):4943
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory