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Psapl1 Gene Detail
Summary
  • Symbol
    Psapl1
  • Name
    prosaposin-like 1
  • Synonyms
    2310020A21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924193
    NCBI Gene: 76943
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:36361365-36363912 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 19.14 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    158 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924193
 protein coding gene Chr5:36361365-36363912 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029487
 protein coding gene Chr5:34525317-34527864 (+)
A/J MGP_AJ_G0029454
 protein coding gene Chr5:33400761-33403307 (+)
AKR/J MGP_AKRJ_G0029403
 protein coding gene Chr5:34664433-34666979 (+)
BALB/cJ MGP_BALBcJ_G0029464
 protein coding gene Chr5:33906783-33909329 (+)
C3H/HeJ MGP_C3HHeJ_G0029186
 protein coding gene Chr5:34682026-34684572 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029918
 protein coding gene Chr5:36427634-36430181 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027155
 protein coding gene Chr5:31146630-31149188 (+)
CAST/EiJ MGP_CASTEiJ_G0028595
 protein coding gene Chr5:33786580-33789128 (+)
CBA/J MGP_CBAJ_G0029154
 protein coding gene Chr5:37295637-37298183 (+)
DBA/2J MGP_DBA2J_G0029302
 protein coding gene Chr5:33538538-33541084 (+)
FVB/NJ MGP_FVBNJ_G0029261
 protein coding gene Chr5:33015097-33017643 (+)
LP/J MGP_LPJ_G0029387
 protein coding gene Chr5:34961474-34964021 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029291
 protein coding gene Chr5:38067798-38070344 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029951
 protein coding gene Chr5:34160461-34163008 (+)
PWK/PhJ MGP_PWKPhJ_G0028320
 protein coding gene Chr5:32709528-32712073 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028151
 protein coding gene Chr5:33623072-33625628 (+)
WSB/EiJ MGP_WSBEiJ_G0028676
 protein coding gene Chr5:34227014-34229560 (+)



Homology
more
  • Human Ortholog
    PSAPL1, prosaposin like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PSAPL1, prosaposin like 1
  • Links
    NCBI Gene ID: 768239
    neXtProt AC: NX_Q6NUJ1
    UniProt: Q6NUJ1

  • Chr Location
    4p16.1; chr4:7430285-7434930 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    23 phenotype references
  • All Mutations and Alleles
    10
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Radiation induced
    4
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    8 involving Psapl1
  • Incidental Mutations
    Mutagenetix , APF
  • Find Mice (IMSR)
    17 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    738
  • Tissues
    7
  • cDNA Data
    34
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76943 NCBI Gene Model | MGI Sequence Detail 2548 C57BL/6J ±  kb
transcript NM_175249 RefSeq | MGI Sequence Detail 2512 C57BL/6  
polypeptide Q8C1C1 UniProt | EBI | MGI Sequence Detail 522 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    Genomic 1
    cDNA 34

    Microarray probesets 2
References
more
  • Summaries
    All 44
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 5
    Phenotypes 23
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory