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Tmem72 Gene Detail
Summary
  • Symbol
    Tmem72
  • Name
    transmembrane protein 72
  • Synonyms
    C230095G01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:2442707
    NCBI Gene: 319776
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:116668500-116693943 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 53.84 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1189 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2442707
 protein coding gene Chr6:116656024-116693943 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031176
 protein coding gene Chr6:119384897-119407738 (-)
A/J MGP_AJ_G0031146
 protein coding gene Chr6:114808891-114830553 (-)
AKR/J MGP_AKRJ_G0031076
 protein coding gene Chr6:117892519-117914760 (-)
BALB/cJ MGP_BALBcJ_G0031156
 protein coding gene Chr6:114606928-114629011 (-)
C3H/HeJ MGP_C3HHeJ_G0030553
 protein coding gene Chr6:66382952-66405267 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031614
 protein coding gene Chr6:122451162-122473985 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028779
 protein coding gene Chr6:111810789-111832807 (-)
CAST/EiJ MGP_CASTEiJ_G0030263
 protein coding gene Chr6:118272519-118295376 (-)
CBA/J MGP_CBAJ_G0030840
 protein coding gene Chr6:127265872-127296327 (-)
DBA/2J MGP_DBA2J_G0030996
 protein coding gene Chr6:113723770-113746726 (-)
FVB/NJ MGP_FVBNJ_G0030948
 protein coding gene Chr6:112896359-112918054 (-)
LP/J MGP_LPJ_G0031074
 protein coding gene Chr6:119411162-119433444 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030982
 protein coding gene Chr6:131415113-131440144 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031643
 protein coding gene Chr6:117925875-117950498 (-)
PWK/PhJ MGP_PWKPhJ_G0029979
 protein coding gene Chr6:112733473-112759640 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029807
 protein coding gene Chr6:116670144-116693556 (-)
WSB/EiJ MGP_WSBEiJ_G0030346
 protein coding gene Chr6:118199749-118225619 (-)



Homology
more
  • Human Ortholog
    TMEM72, transmembrane protein 72
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM72, transmembrane protein 72
  • Synonyms
    C10orf127, KSP37
  • Links
    NCBI Gene ID: 643236
    neXtProt AC: NX_A0PK05
    UniProt: A0PK05

  • Chr Location
    10q11.21; chr10:44911316-44937010 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    751
  • Tissues
    27
  • cDNA Data
    15
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 319776 NCBI Gene Model | MGI Sequence Detail 25444 C57BL/6J ±  kb
    transcript NM_178768 RefSeq | MGI Sequence Detail 3335 C57BL/6  
    polypeptide Q8C3K5 UniProt | EBI | MGI Sequence Detail 275 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 2
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 3
      Gene Ontology 1
      Phenotypes 8
    • Earliest
      J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/22/2024
    MGI 6.24     		The Jackson Laboratory