About   Help   FAQ
Ccdc134 Gene Detail
Summary
  • Symbol
    Ccdc134
  • Name
    coiled-coil domain containing 134
  • Synonyms
    2310042L06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923707
    NCBI Gene: 76457
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:82012123-82026404 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 38.47 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    404 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923707
 protein coding gene Chr15:82012101-82026404 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022134
 protein coding gene Chr15:82616205-82631908 (+)
A/J MGP_AJ_G0022094
 protein coding gene Chr15:79694284-79708597 (+)
AKR/J MGP_AKRJ_G0022070
 protein coding gene Chr15:81900829-81918634 (+)
BALB/cJ MGP_BALBcJ_G0022100
 protein coding gene Chr15:79745133-79759386 (+)
C3H/HeJ MGP_C3HHeJ_G0021871
 protein coding gene Chr15:81920339-81934547 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022543
 protein coding gene Chr15:85856637-85871878 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020072
 protein coding gene Chr15:76134231-76148332 (+)
CAST/EiJ MGP_CASTEiJ_G0021391
 protein coding gene Chr15:82715513-82730119 (+)
CBA/J MGP_CBAJ_G0021836
 protein coding gene Chr15:88540537-88554793 (+)
DBA/2J MGP_DBA2J_G0021964
 protein coding gene Chr15:79168221-79182510 (+)
FVB/NJ MGP_FVBNJ_G0021941
 protein coding gene Chr15:78224735-78239031 (+)
LP/J MGP_LPJ_G0022033
 protein coding gene Chr15:82765097-82779354 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021962
 protein coding gene Chr15:93455129-93469421 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022557
 protein coding gene Chr15:82011818-82026513 (+)
PWK/PhJ MGP_PWKPhJ_G0021133
 protein coding gene Chr15:79218513-79233192 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020972
 protein coding gene Chr15:81796178-81812066 (+)
WSB/EiJ MGP_WSBEiJ_G0021442
 protein coding gene Chr15:82427552-82443237 (+)



Homology
more
  • Human Ortholog
    CCDC134, coiled-coil domain containing 134
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CCDC134, coiled-coil domain containing 134
  • Synonyms
    OI22
  • Links
    NCBI Gene ID: 79879
    neXtProt AC: NX_Q9H6E4
    UniProt: Q9H6E4

  • Chr Location
    22q13.2; chr22:41800679-41832164 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CCDC134 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 2 alleles in 2 genetic backgrounds
    30 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele display embryonic lethality during organogenesis with impaired liver and vascular development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    738
  • Tissues
    15
  • cDNA Data
    43
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000068114 Ensembl Gene Model | MGI Sequence Detail 14282 C57BL/6J ±  kb
    transcript ENSMUST00000089174 Ensembl | MGI Sequence Detail 2046 Not Applicable  
    polypeptide ENSMUSP00000086578 Ensembl | MGI Sequence Detail 229 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000029316 coiled-coil domain-containing protein 134
      (term hierarchy)
    • InterPro Domains
      IPR026321 Coiled-coil domain-containing protein 134
    • GlyGen
      Q8C7V8 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 45
      cDNA 43
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2146205
    References
    more
    • Summaries
      All 55
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 4
      Phenotypes 30
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory