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Amer2 Gene Detail
Summary
  • Symbol
    Amer2
  • Name
    APC membrane recruitment 2
  • Synonyms
    2600011E07Rik, Amer2, Fam123a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919375
    NCBI Gene: 72125
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:60615141-60625642 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 31.62 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    228 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919375
 protein coding gene Chr14:60610708-60625646 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021432
 protein coding gene Chr14:54717639-54720355 (+)
A/J MGP_AJ_G0021391
 protein coding gene Chr14:53528265-53530976 (+)
AKR/J MGP_AKRJ_G0021366
 protein coding gene Chr14:55431804-55434515 (+)
BALB/cJ MGP_BALBcJ_G0021396
 protein coding gene Chr14:53493037-53495745 (+)
C3H/HeJ MGP_C3HHeJ_G0021174
 protein coding gene Chr14:55099546-55102262 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021835
 protein coding gene Chr14:57396344-57399061 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019375
 protein coding gene Chr14:51562276-51564971 (+)
CAST/EiJ MGP_CASTEiJ_G0020690
 protein coding gene Chr14:51485332-51488043 (+)
CBA/J MGP_CBAJ_G0021141
 protein coding gene Chr14:59044531-59047242 (+)
DBA/2J MGP_DBA2J_G0021264
 protein coding gene Chr14:53206486-53209202 (+)
FVB/NJ MGP_FVBNJ_G0021242
 protein coding gene Chr14:52623044-52625760 (+)
LP/J MGP_LPJ_G0021338
 protein coding gene Chr14:55758183-55760899 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021271
 protein coding gene Chr14:58410347-58413166 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021858
 protein coding gene Chr14:54589702-54592418 (+)
PWK/PhJ MGP_PWKPhJ_G0020434
 protein coding gene Chr14:49862025-49864838 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020267
 protein coding gene Chr14:50552871-50555570 (+)
WSB/EiJ MGP_WSBEiJ_G0020743
 protein coding gene Chr14:54906817-54909577 (+)



Homology
more
  • Human Ortholog
    AMER2, APC membrane recruitment protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AMER2, APC membrane recruitment protein 2
  • Synonyms
    FAM123A
  • Links
    NCBI Gene ID: 219287
    neXtProt AC: NX_Q8N7J2
    UniProt: Q8N7J2

  • Chr Location
    13q12.13; chr13:25161679-25172288 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Targeted
    1
  • Genomic Mutations
    1 involving Amer2
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    30 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    890
  • Tissues
    93
  • cDNA Data
    14
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 72125 NCBI Gene Model | MGI Sequence Detail 10502 C57BL/6J ±  kb
transcript NM_028113 RefSeq | MGI Sequence Detail 10502 C57BL/6  
polypeptide Q8CCJ4 UniProt | EBI | MGI Sequence Detail 672 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory