About   Help   FAQ
Klf17 Gene Detail
Summary
  • Symbol
    Klf17
  • Name
    Kruppel-like transcription factor 17
  • Synonyms
    7420700M05Rik, D4Ertd561e, Zfp393
  • Feature Type
    protein coding gene
  • IDs
    MGI:2181068
    NCBI Gene: 75753
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:117615033-117622845 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 53.46 cM, cytoband D1
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    374 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2181068
 protein coding gene Chr4:117613856-117622863 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028654
 protein coding gene Chr4:118750764-118759447 (-)
A/J MGP_AJ_G0028615
 protein coding gene Chr4:114172247-114180337 (-)
AKR/J MGP_AKRJ_G0028565
 protein coding gene Chr4:116668861-116676996 (-)
BALB/cJ MGP_BALBcJ_G0028636
 protein coding gene Chr4:114796497-114804265 (-)
C3H/HeJ MGP_C3HHeJ_G0028350
 protein coding gene Chr4:118251379-118260034 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029077
 protein coding gene Chr4:123325432-123338834 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026361
 protein coding gene Chr4:108198917-108207545 (-)
CAST/EiJ MGP_CASTEiJ_G0027784
 protein coding gene Chr4:115475144-115484127 (-)
CBA/J MGP_CBAJ_G0028317
 protein coding gene Chr4:126696209-126706946 (-)
DBA/2J MGP_DBA2J_G0028465
 protein coding gene Chr4:114788474-114799864 (-)
FVB/NJ MGP_FVBNJ_G0028433
 protein coding gene Chr4:113305821-113313772 (-)
LP/J MGP_LPJ_G0028567
 protein coding gene Chr4:118937792-118949182 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028460
 protein coding gene Chr4:131620006-131631065 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029114
 protein coding gene Chr4:117815762-117824856 (-)
PWK/PhJ MGP_PWKPhJ_G0027510
 protein coding gene Chr4:111609581-111617867 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027333
 protein coding gene Chr4:114135930-114143953 (-)
WSB/EiJ MGP_WSBEiJ_G0027863
 protein coding gene Chr4:117704883-117713511 (-)



Homology
more
  • Human Ortholog
    KLF17, KLF transcription factor 17
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KLF17, KLF transcription factor 17
  • Synonyms
    Zfp393, ZLF393, ZNF393
  • Links
    NCBI Gene ID: 128209
    neXtProt AC: NX_Q5JT82
    UniProt: Q5JT82

  • Chr Location
    1p34.1; chr1:44043927-44135140 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    776
  • Tissues
    46
  • cDNA Data
    180
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000048626 Ensembl Gene Model | MGI Sequence Detail 7813 C57BL/6J ±  kb
transcript ENSMUST00000062747 Ensembl | MGI Sequence Detail 2400 Not Applicable  
polypeptide ENSMUSP00000052316 Ensembl | MGI Sequence Detail 341 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 184
    cDNA 180
    Primer pair 4

    Microarray probesets 6
Other
Accession IDs
less
MGI:1261762, MGI:1923003, MGI:2138777, MGI:2140488, MGI:2140697
References
more
  • Summaries
    All 52
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 14
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:346059 Hu Y, et al., Maternal KLF17 controls zygotic genome activation by acting as a messenger for RNA Pol II recruitment in mouse embryos. Dev Cell. 2024 Mar 11;59(5):613-626.e6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory