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Ifi205 Gene Detail
Summary
  • Symbol
    Ifi205
  • Name
    interferon activated gene 205
  • Synonyms
    D3
  • Feature Type
    protein coding gene
  • IDs
    MGI:101847
    NCBI Gene: 226695
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:173839564-173859376 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 80.83 cM, cytoband H3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    242 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_101847
 protein coding gene Chr1:173839549-173859617 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016819
 protein coding gene Chr1:180010771-180068773 (-)
A/J no annotation
AKR/J MGP_AKRJ_G0016763
 protein coding gene Chr1:177923319-177985185 (-)
BALB/cJ MGP_BALBcJ_G0016752
 protein coding gene Chr1:172975367-173284825 (-)
C3H/HeJ MGP_C3HHeJ_G0016580
 protein coding gene Chr1:178586587-178594835 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017218
 protein coding gene Chr1:186068896-186105573 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014926
 protein coding gene Chr1:164223603-164237109 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0016553
 protein coding gene Chr1:192813118-192834675 (-)
DBA/2J MGP_DBA2J_G0016659
 protein coding gene Chr1:171700812-171715007 (-)
FVB/NJ MGP_FVBNJ_G0016656
 protein coding gene Chr1:169772749-169792713 (-)
LP/J MGP_LPJ_G0016734
 protein coding gene Chr1:181094908-181163100 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016685
 protein coding gene Chr1:199761661-199985787 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017253
 protein coding gene Chr1:177789221-177813021 (-)
PWK/PhJ MGP_PWKPhJ_G0015948
 protein coding gene Chr1:170776020-170789800 (-)
SPRET/EiJ no annotation
WSB/EiJ MGP_WSBEiJ_G0016219
 protein coding gene Chr1:177590124-177945002 (-)



Homology
more
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IFI16, interferon gamma inducible protein 16
  • Synonyms
    IFNGIP1, PYHIN2
  • Links
    NCBI Gene ID: 3428
    neXtProt AC: NX_Q16666
    UniProt: Q16666

  • Chr Location
    1q23.1; chr1:158999968-159055155 (+)  GRCh38
  • Human Ortholog
    MNDA, myeloid cell nuclear differentiation antigen
  • Synonyms
    PYHIN3
  • Links
    NCBI Gene ID: 4332
    neXtProt AC: NX_P41218
    UniProt: P41218

  • Chr Location
    1q23.1; chr1:158831351-158849506 (+)  GRCh38
  • Human Ortholog
    PYHIN1, pyrin and HIN domain family member 1
  • Synonyms
    IFIX
  • Links
    NCBI Gene ID: 149628
    neXtProt AC: NX_Q6K0P9
    UniProt: Q6K0P9

  • Chr Location
    1q23.1; chr1:158930796-158990870 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    937
  • Tissues
    119
  • cDNA Data
    15
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054203 Ensembl Gene Model | MGI Sequence Detail 19813 C57BL/6J ±  kb
transcript ENSMUST00000059226 Ensembl | MGI Sequence Detail 1613 Not Applicable  
polypeptide ENSMUSP00000062409 Ensembl | MGI Sequence Detail 404 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 19

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-18669
References
more
  • Summaries
    All 40
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:16675 Tannenbaum CS, et al., Characterization of lipopolysaccharide-induced macrophage gene expression. J Immunol. 1988 May 15;140(10):3640-5
  • Latest
    J:329937 Maltbaek JH, et al., ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP. Immunity. 2022 Oct 11;55(10):1799-1812.e4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory