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Dmrtc2 Gene Detail
Summary
  • Symbol
    Dmrtc2
  • Name
    doublesex and mab-3 related transcription factor like family C2
  • Synonyms
    4933432E21Rik, Dmrt7
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918491
    NCBI Gene: 71241
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:24569482-24577076 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 13.33 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    239 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918491
 protein coding gene Chr7:24569242-24577080 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031845
 protein coding gene Chr7:23280463-23287983 (+)
A/J MGP_AJ_G0031824
 protein coding gene Chr7:22706971-22714481 (+)
AKR/J MGP_AKRJ_G0031753
 protein coding gene Chr7:23234300-23243381 (+)
BALB/cJ MGP_BALBcJ_G0031832
 protein coding gene Chr7:22912554-22920335 (+)
C3H/HeJ MGP_C3HHeJ_G0031550
 protein coding gene Chr7:23650455-23659541 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032293
 protein coding gene Chr7:24049819-24058949 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029348
 protein coding gene Chr7:24141013-24148578 (+)
CAST/EiJ MGP_CASTEiJ_G0030890
 protein coding gene Chr7:17128856-17136489 (+)
CBA/J MGP_CBAJ_G0031515
 protein coding gene Chr7:24929193-24938935 (+)
DBA/2J MGP_DBA2J_G0031669
 protein coding gene Chr7:22611773-22619664 (+)
FVB/NJ MGP_FVBNJ_G0031622
 protein coding gene Chr7:22587335-22596690 (+)
LP/J MGP_LPJ_G0031748
 protein coding gene Chr7:23589987-23597790 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031659
 protein coding gene Chr7:24672488-24681701 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032325
 protein coding gene Chr7:22938261-22945739 (+)
PWK/PhJ MGP_PWKPhJ_G0030614
 protein coding gene Chr7:17540475-17548194 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030445
 protein coding gene Chr7:14249398-14256951 (+)
WSB/EiJ MGP_WSBEiJ_G0030994
 protein coding gene Chr7:23095339-23103555 (+)



Homology
more
  • Human Ortholog
    DMRTC2, DMRT like family C2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DMRTC2, DMRT like family C2
  • Links
    NCBI Gene ID: 63946
    neXtProt AC: NX_Q8IXT2
    UniProt: Q8IXT2

  • Chr Location
    19q13.2; chr19:41844743-41852333 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    17 phenotypes from 3 alleles in 2 genetic backgrounds
    1 images
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Males homozygous for a targeted allele are sterile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    924
  • Tissues
    155
  • cDNA Data
    11
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000011349 Ensembl Gene Model | MGI Sequence Detail 7595 C57BL/6J ±  kb
    transcript ENSMUST00000011493 Ensembl | MGI Sequence Detail 1619 Not Applicable  
    polypeptide ENSMUSP00000011493 Ensembl | MGI Sequence Detail 370 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 22
      cDNA 11
      Primer pair 7
      Other 4

      Microarray probesets 2
    References
    more
    • Summaries
      All 41
      Developmental Gene Expression 9
      Gene Ontology 9
      Phenotypes 6
    • Earliest
      J:68323 Carninci P, et al., Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Genome Res. 2000 Oct;10(10):1617-30
    • Latest
      J:307968 He Y, et al., Single-cell RNA-Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation. Aging Cell. 2021 Jul;20(7):e13424
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory