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Bag5 Gene Detail
Summary
  • Symbol
    Bag5
  • Name
    BCL2-associated athanogene 5
  • Synonyms
    1600025G07Rik, 4930405J06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917619
    NCBI Gene: 70369
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:111675922-111679690 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 61.11 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    197 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917619
 protein coding gene Chr12:111675922-111679691 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020139
 protein coding gene Chr12:114112836-114116604 (-)
A/J MGP_AJ_G0020095
 protein coding gene Chr12:109732218-109735966 (-)
AKR/J MGP_AKRJ_G0020070
 protein coding gene Chr12:112873057-112876805 (-)
BALB/cJ MGP_BALBcJ_G0020080
 protein coding gene Chr12:110156046-110159812 (-)
C3H/HeJ MGP_C3HHeJ_G0019882
 protein coding gene Chr12:113374785-113378533 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020525
 protein coding gene Chr12:117660104-117663871 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018138
 protein coding gene Chr12:106170769-106174539 (-)
CAST/EiJ MGP_CASTEiJ_G0019423
 protein coding gene Chr12:108217670-108221427 (-)
CBA/J MGP_CBAJ_G0019849
 protein coding gene Chr12:122128422-122132170 (-)
DBA/2J MGP_DBA2J_G0019966
 protein coding gene Chr12:109208709-109212457 (-)
FVB/NJ MGP_FVBNJ_G0019951
 protein coding gene Chr12:108015357-108019106 (-)
LP/J MGP_LPJ_G0020041
 protein coding gene Chr12:113939061-113942827 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019989
 protein coding gene Chr12:125266536-125270284 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020554
 protein coding gene Chr12:112393381-112397130 (-)
PWK/PhJ MGP_PWKPhJ_G0019184
 protein coding gene Chr12:103853978-103858241 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018987
 protein coding gene Chr12:106562269-106566030 (-)
WSB/EiJ MGP_WSBEiJ_G0019482
 protein coding gene Chr12:113304031-113307779 (-)



Homology
more
  • Human Ortholog
    BAG5, BAG cochaperone 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BAG5, BAG cochaperone 5
  • Synonyms
    BAG-5, CMD2F
  • Links
    NCBI Gene ID: 9529
    neXtProt AC: NX_Q9UL15
    UniProt: Q9UL15

  • Chr Location
    14q32.33; chr14:103556545-103562657 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Bag5 mouse models; 1 with human BAG5 associations

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    51
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    57
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70369 NCBI Gene Model | MGI Sequence Detail 3769 C57BL/6J ±  kb
    transcript NM_001324480 RefSeq | MGI Sequence Detail 2306 C57BL/6  
    polypeptide Q8CI32 UniProt | EBI | MGI Sequence Detail 447 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 58
      cDNA 58

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1922041
    References
    more
    • Summaries
      All 38
      Diseases 1
      Gene Ontology 8
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:350804 Gan S, et al., BAG5 regulates HSPA8-mediated protein folding required for sperm head-tail coupling apparatus assembly. EMBO Rep. 2024 Apr;25(4):2045-2070
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/29/2024
    MGI 6.24     		The Jackson Laboratory