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Lrrc45 Gene Detail
Summary
  • Symbol
    Lrrc45
  • Name
    leucine rich repeat containing 45
  • Synonyms
    MGC:30595
  • Feature Type
    protein coding gene
  • IDs
    MGI:2387183
    NCBI Gene: 217366
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120604779-120611954 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 84.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2387183
 protein coding gene Chr11:120604751-120611954 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019523
 protein coding gene Chr11:125198838-125206036 (+)
A/J MGP_AJ_G0019491
 protein coding gene Chr11:119624237-119631441 (+)
AKR/J MGP_AKRJ_G0019461
 protein coding gene Chr11:123241470-123248668 (+)
BALB/cJ MGP_BALBcJ_G0019466
 protein coding gene Chr11:119983805-119990998 (+)
C3H/HeJ MGP_C3HHeJ_G0019272
 protein coding gene Chr11:123565302-123572500 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019914
 protein coding gene Chr11:128984641-128991837 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017540
 protein coding gene Chr11:116614808-116621994 (+)
CAST/EiJ MGP_CASTEiJ_G0018826
 protein coding gene Chr11:125070699-125077909 (+)
CBA/J MGP_CBAJ_G0019243
 protein coding gene Chr11:134020639-134027827 (+)
DBA/2J MGP_DBA2J_G0019355
 protein coding gene Chr11:118992296-118999504 (+)
FVB/NJ MGP_FVBNJ_G0019347
 protein coding gene Chr11:118706824-118714011 (+)
LP/J MGP_LPJ_G0019427
 protein coding gene Chr11:125499874-125507567 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019380
 protein coding gene Chr11:132857930-132865133 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019954
 protein coding gene Chr11:123910501-123917694 (+)
PWK/PhJ MGP_PWKPhJ_G0018592
 protein coding gene Chr11:120437108-120444305 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018384
 protein coding gene Chr11:123680200-123687351 (+)
WSB/EiJ MGP_WSBEiJ_G0018878
 protein coding gene Chr11:123907577-123914761 (+)



Homology
more
  • Human Ortholog
    LRRC45, leucine rich repeat containing 45
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC45, leucine rich repeat containing 45
  • Links
    NCBI Gene ID: 201255
    neXtProt AC: NX_Q96CN5
    UniProt: Q96CN5

  • Chr Location
    17q25.3; chr17:82023305-82031151 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    59
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 217366 NCBI Gene Model | MGI Sequence Detail 7176 C57BL/6J ±  kb
transcript NM_153545 RefSeq | MGI Sequence Detail 2476 C57BL/6  
polypeptide Q8CIM1 UniProt | EBI | MGI Sequence Detail 670 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 59

    Microarray probesets 3
References
more
  • Summaries
    All 27
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 2
  • Earliest
    J:82808 Strausberg RL, et al., Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903
  • Latest
    J:343289 Ho KH, et al., Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/22/2024
MGI 6.24 		The Jackson Laboratory