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H1f7 Gene Detail
Summary
  • Symbol
    H1f7
  • Name
    H1.7 linker histone
  • Synonyms
    1700026P10Rik, H1-7, H1fnt, H1T2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917319
    NCBI Gene: 70069
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:98153867-98155174 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 54.26 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    127 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917319
 protein coding gene Chr15:98153863-98155188 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022290
 protein coding gene Chr15:99957801-99959126 (-)
A/J MGP_AJ_G0022249
 protein coding gene Chr15:96005655-96006980 (-)
AKR/J MGP_AKRJ_G0022224
 protein coding gene Chr15:98909065-98910390 (-)
BALB/cJ MGP_BALBcJ_G0022255
 protein coding gene Chr15:96225424-96226749 (-)
C3H/HeJ MGP_C3HHeJ_G0022025
 protein coding gene Chr15:98971926-98973251 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022700
 protein coding gene Chr15:103655885-103657210 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020226
 protein coding gene Chr15:91950811-91952152 (-)
CAST/EiJ MGP_CASTEiJ_G0021546
 protein coding gene Chr15:99855323-99856660 (-)
CBA/J MGP_CBAJ_G0021992
 protein coding gene Chr15:107127820-107129145 (-)
DBA/2J MGP_DBA2J_G0022119
 protein coding gene Chr15:95451765-95453090 (-)
FVB/NJ MGP_FVBNJ_G0022098
 protein coding gene Chr15:94450585-94451911 (-)
LP/J MGP_LPJ_G0022190
 protein coding gene Chr15:100077273-100078598 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022118
 protein coding gene Chr15:111217437-111218762 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022715
 protein coding gene Chr15:99048989-99050314 (-)
PWK/PhJ MGP_PWKPhJ_G0021288
 protein coding gene Chr15:95561379-95562704 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021122
 protein coding gene Chr15:98836667-98837980 (-)
WSB/EiJ MGP_WSBEiJ_G0021596
 protein coding gene Chr15:99568891-99570216 (-)



Homology
more
  • Human Ortholog
    H1-7, H1.7 linker histone
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    H1-7, H1.7 linker histone
  • Synonyms
    H1.7, H1FNT, H1T2
  • Links
    NCBI Gene ID: 341567
    neXtProt AC: NX_Q75WM6
    UniProt: Q75WM6

  • Chr Location
    12q13.11; chr12:48328980-48330279 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 2 alleles in 2 genetic backgrounds
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null male mice display reduced fertility with asthenozoospermia, oligozoospermia, and teratozoospermia.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    1
  • cDNA Data
    14
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000048077 Ensembl Gene Model | MGI Sequence Detail 1308 C57BL/6J ±  kb
    transcript ENSMUST00000060855 Ensembl | MGI Sequence Detail 1308 Not Applicable  
    polypeptide ENSMUSP00000127616 Ensembl | MGI Sequence Detail 398 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 14
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:6325025
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 6
      Phenotypes 24
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory