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Dcun1d3 Gene Detail
Summary
  • Symbol
    Dcun1d3
  • Name
    defective in cullin neddylation 1 domain containing 3
  • Synonyms
    1700020A13Rik, DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae), MGC:40975
  • Feature Type
    protein coding gene
  • IDs
    MGI:2679003
    NCBI Gene: 233805
  • Alliance
    gene page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:119452381-119495553 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 64.27 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    648 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2679003
 protein coding gene Chr7:119452019-119495553 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032920
 protein coding gene Chr7:123788423-123831714 (-)
A/J MGP_AJ_G0032903
 protein coding gene Chr7:120582632-120625760 (-)
AKR/J MGP_AKRJ_G0032835
 protein coding gene Chr7:123698203-123741521 (-)
BALB/cJ MGP_BALBcJ_G0032908
 protein coding gene Chr7:120315149-120359111 (-)
C3H/HeJ MGP_C3HHeJ_G0032618
 protein coding gene Chr7:123601444-123647339 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033414
 protein coding gene Chr7:128683217-128728878 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030386
 protein coding gene Chr7:122015133-122058334 (-)
CAST/EiJ MGP_CASTEiJ_G0031946
 protein coding gene Chr7:115354082-115399507 (-)
CBA/J MGP_CBAJ_G0032591
 protein coding gene Chr7:132978072-133023806 (-)
DBA/2J MGP_DBA2J_G0032743
 protein coding gene Chr7:118631878-118675384 (-)
FVB/NJ MGP_FVBNJ_G0032696
 protein coding gene Chr7:118470747-118515343 (-)
LP/J MGP_LPJ_G0032837
 protein coding gene Chr7:125240807-125285220 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032728
 protein coding gene Chr7:134444101-134487982 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033434
 protein coding gene Chr7:122670629-122715632 (-)
PWK/PhJ MGP_PWKPhJ_G0031654
 protein coding gene Chr7:111549313-111593548 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031500
 protein coding gene Chr7:109427307-109470789 (-)
WSB/EiJ MGP_WSBEiJ_G0032059
 protein coding gene Chr7:123577053-123622276 (-)



Homology
more
  • Human Ortholog
    DCUN1D3, defective in cullin neddylation 1 domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DCUN1D3, defective in cullin neddylation 1 domain containing 3
  • Synonyms
    44M2.4, DCNL3, SCCRO3
  • Links
    NCBI Gene ID: 123879
    neXtProt AC: NX_Q8IWE4
    UniProt: Q8IWE4

  • Chr Location
    16p12.3; chr16:20854925-20900358 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    37
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    810
  • Tissues
    77
  • cDNA Data
    37
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 233805 NCBI Gene Model | MGI Sequence Detail 43173 C57BL/6J ±  kb
    transcript NM_173408 RefSeq | MGI Sequence Detail 5637 C57BL/6  
    polypeptide Q8K0V2 UniProt | EBI | MGI Sequence Detail 304 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 38
      cDNA 37
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1919510
    References
    more
    • Summaries
      All 44
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory