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Ly6g5c Gene Detail
Summary
  • Symbol
    Ly6g5c
  • Name
    lymphocyte antigen 6 family member G5C
  • Synonyms
    G5c, NG33
  • Feature Type
    protein coding gene
  • IDs
    MGI:2148974
    NCBI Gene: 114652
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:35327255-35330967 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 18.59 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2148974
 protein coding gene Chr17:35327255-35331149 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023617
 protein coding gene Chr17:35249507-35253159 (+)
A/J MGP_AJ_G0023577
 protein coding gene Chr17:34081718-34085645 (+)
AKR/J MGP_AKRJ_G0023545
 protein coding gene Chr17:34556707-34560499 (+)
BALB/cJ MGP_BALBcJ_G0023583
 protein coding gene Chr17:34219414-34224310 (+)
C3H/HeJ MGP_C3HHeJ_G0023344
 protein coding gene Chr17:34956616-34960399 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024022
 protein coding gene Chr17:36589115-36592812 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021503
 protein coding gene Chr17:31850101-31853928 (+)
CAST/EiJ MGP_CASTEiJ_G0022840
 protein coding gene Chr17:34953798-34957676 (+)
CBA/J MGP_CBAJ_G0023322
 protein coding gene Chr17:38092325-38096060 (+)
DBA/2J MGP_DBA2J_G0023450
 protein coding gene Chr17:33404300-33409404 (+)
FVB/NJ MGP_FVBNJ_G0023417
 protein coding gene Chr17:33243593-33247345 (+)
LP/J MGP_LPJ_G0023527
 protein coding gene Chr17:35576865-35581127 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023439
 protein coding gene Chr17:37030291-37034025 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024067
 protein coding gene Chr17:34775923-34780627 (+)
PWK/PhJ MGP_PWKPhJ_G0022588
 protein coding gene Chr17:32238571-32242580 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022408
 protein coding gene Chr17:32791510-32795177 (+)
WSB/EiJ MGP_WSBEiJ_G0022904
 protein coding gene Chr17:34896780-34900459 (+)



Homology
more
  • Human Ortholog
    LY6G5C, lymphocyte antigen 6 family member G5C
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LY6G5C, lymphocyte antigen 6 family member G5C
  • Synonyms
    C6orf20, G5C, LY6G5CA, LY6G5CB, NG33
  • Links
    NCBI Gene ID: 80741
    neXtProt AC: NX_Q5SRR4
    UniProt: Q5SRR4

  • Chr Location
    6p21.33; chr6:31676684-31684040 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
  • All Mutations and Alleles
    5
  • Endonuclease-mediated
    2
  • Gene trapped
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Ly6g5c
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    8 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    7
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034482 Ensembl Gene Model | MGI Sequence Detail 3713 C57BL/6J ±  kb
transcript ENSMUST00000037849 Ensembl | MGI Sequence Detail 509 Not Applicable  
polypeptide ENSMUSP00000039151 Ensembl | MGI Sequence Detail 149 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    Genomic 1
    cDNA 5
    Primer pair 2

    Microarray probesets 1
References
more
  • Summaries
    All 23
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:63110 Allcock RJ, et al., The mouse as a model for the effects of MHC genes on human disease. Immunol Today. 2000 Jul;21(7):328-32
  • Latest
    J:340906 Sakurai N, et al., CRISPR/Cas9-mediated disruption of lipocalins, Ly6g5b, and Ly6g5c causes male subfertility in mice. Andrology. 2022 Nov 25;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory