About   Help   FAQ
Polr3gl Gene Detail
Summary
  • Symbol
    Polr3gl
  • Name
    polymerase (RNA) III (DNA directed) polypeptide G like
  • Synonyms
    2010003I19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917120
    NCBI Gene: 69870
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:96485188-96501497 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 41.93 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    428 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917120
 protein coding gene Chr3:96485188-96501497 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027621
 protein coding gene Chr3:97456799-97461149 (-)
A/J MGP_AJ_G0027583
 protein coding gene Chr3:94340178-94356503 (-)
AKR/J MGP_AKRJ_G0027550
 protein coding gene Chr3:96560816-96578398 (-)
BALB/cJ MGP_BALBcJ_G0027593
 protein coding gene Chr3:94152000-94168319 (-)
C3H/HeJ MGP_C3HHeJ_G0027325
 protein coding gene Chr3:96863364-96868536 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028039
 protein coding gene Chr3:101009247-101028064 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025380
 protein coding gene Chr3:90621949-90637605 (-)
CAST/EiJ MGP_CASTEiJ_G0026780
 protein coding gene Chr3:96121123-96139130 (-)
CBA/J MGP_CBAJ_G0027300
 protein coding gene Chr3:104706598-104710948 (-)
DBA/2J MGP_DBA2J_G0027443
 protein coding gene Chr3:93673144-93689750 (-)
FVB/NJ MGP_FVBNJ_G0027412
 protein coding gene Chr3:91683779-91700032 (-)
LP/J MGP_LPJ_G0027548
 protein coding gene Chr3:98742227-98757984 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027438
 protein coding gene Chr3:110778372-110784166 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028093
 protein coding gene Chr3:96180459-96196244 (-)
PWK/PhJ MGP_PWKPhJ_G0026505
 protein coding gene Chr3:93507011-93523791 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026327
 protein coding gene Chr3:94483814-94499833 (-)
WSB/EiJ MGP_WSBEiJ_G0026858
 protein coding gene Chr3:96629906-96645728 (-)



Homology
more
  • Human Ortholog
    POLR3GL, RNA polymerase III subunit GL
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    POLR3GL, RNA polymerase III subunit GL
  • Synonyms
    flj32422, RPC32HOM, SOFM
  • Links
    NCBI Gene ID: 84265
    neXtProt AC: NX_Q9BT43
    UniProt: Q9BT43

  • Chr Location
    1q21.1; chr1:145964690-145978848 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit severe growth retardation, impaired balance, ataxia, and postnatal lethality.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    20
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69870 NCBI Gene Model | MGI Sequence Detail 16310 C57BL/6J ±  kb
    transcript NM_027241 RefSeq | MGI Sequence Detail 1427 C57BL/6  
    polypeptide Q8R0C0 UniProt | EBI | MGI Sequence Detail 218 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000013007 DNA-directed RNA polymerase III subunit RPC7-like
      (term hierarchy)
    • InterPro Domains
      IPR024661 DNA-directed RNA polymerase III, subunit Rpc31
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 20

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2139630
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 4
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    10/22/2024
    MGI 6.24     		The Jackson Laboratory