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Slc25a42 Gene Detail
Summary
  • Symbol
    Slc25a42
  • Name
    solute carrier family 25, member 42
  • Synonyms
    2900084M01Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920345
    NCBI Gene: 73095
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:70636990-70664931 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.15 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    582 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920345
 protein coding gene Chr8:70636990-70664955 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033695
 protein coding gene Chr8:70441584-70473669 (-)
A/J MGP_AJ_G0033678
 protein coding gene Chr8:67573455-67603331 (-)
AKR/J MGP_AKRJ_G0033603
 protein coding gene Chr8:69497001-69524143 (-)
BALB/cJ MGP_BALBcJ_G0033674
 protein coding gene Chr8:67800901-67829113 (-)
C3H/HeJ MGP_C3HHeJ_G0033384
 protein coding gene Chr8:70144400-70174730 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034191
 protein coding gene Chr8:73106560-73137109 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031135
 protein coding gene Chr8:62391676-62419484 (-)
CAST/EiJ MGP_CASTEiJ_G0032709
 protein coding gene Chr8:69623239-69655077 (-)
CBA/J MGP_CBAJ_G0033362
 protein coding gene Chr8:75741224-75768527 (-)
DBA/2J MGP_DBA2J_G0033516
 protein coding gene Chr8:67299935-67327472 (-)
FVB/NJ MGP_FVBNJ_G0033457
 protein coding gene Chr8:66402530-66432285 (-)
LP/J MGP_LPJ_G0033603
 protein coding gene Chr8:70472853-70499863 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033500
 protein coding gene Chr8:78401674-78429797 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034209
 protein coding gene Chr8:69681302-69708704 (-)
PWK/PhJ MGP_PWKPhJ_G0032417
 protein coding gene Chr8:66589102-66617752 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032253
 protein coding gene Chr8:68649259-68679118 (-)
WSB/EiJ MGP_WSBEiJ_G0032824
 protein coding gene Chr8:70041605-70073635 (-)



Homology
more
  • Human Ortholog
    SLC25A42, solute carrier family 25 member 42
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC25A42, solute carrier family 25 member 42
  • Synonyms
    MECREN
  • Links
    NCBI Gene ID: 284439
    neXtProt AC: NX_Q86VD7
    UniProt: Q86VD7

  • Chr Location
    19p13.11; chr19:19063994-19113030 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    30
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 73095 NCBI Gene Model | MGI Sequence Detail 27942 C57BL/6J ±  kb
    transcript NM_001007570 RefSeq | MGI Sequence Detail 3181 C57BL/6  
    polypeptide Q8R0Y8 UniProt | EBI | MGI Sequence Detail 318 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000031993 solute carrier family 25 member 42
      (term hierarchy)
    • InterPro Domains
      IPR014762 DNA mismatch repair, conserved site
      IPR023395 Mitochondrial carrier domain superfamily
      IPR002067 Mitochondrial carrier protein
      IPR018108 Mitochondrial substrate/solute carrier
      IPR002167 Solute carrier family 25 member 16-like
    • GlyGen
      Q8R0Y8 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 31
      cDNA 30
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 33
      Gene Ontology 6
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory