Mptx1 MGI Mouse Gene Detail - MGI:1913539

Symbol

Mptx1
Name

mucosal pentraxin 1
Synonyms

1810030J14Rik

Feature Type

protein coding gene
IDs

MGI:1913539
NCBI Gene: 66289
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr1:174158084-174160439 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 81.01 cM
Mapping Data

3 experiments

SNPs within 2kb

298 from dbSNP Build 142
Strain Annotations

8

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1913539	protein coding gene	Chr1:174158084-174160443 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0016805	protein coding gene	Chr1:179198063-179201978 (-)
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	MGP_C57BL6NJ_G0017230	protein coding gene	Chr1:186430462-186432811 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0016171	protein coding gene	Chr1:178248109-178251039 (+)
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	MGP_NZOHlLtJ_G0017265	protein coding gene	Chr1:178097863-178100450 (+)
PWK/PhJ	MGP_PWKPhJ_G0015934	protein coding gene	Chr1:170178455-170179169 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0015736	protein coding gene	Chr1:177122230-177124587 (+)
WSB/EiJ	MGP_WSBEiJ_G0016211	protein coding gene	Chr1:177067089-177070472 (-)

Human Ortholog

MPTX1, mucosal pentraxin 1 (pseudogene)

Vertebrate Orthologs

6

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

MPTX1, mucosal pentraxin 1 (pseudogene)
Synonyms

MPTX
Links

HGNC:48364

NCBI Gene ID: 649458

UniProt: A8MV57
Chr Location

chr1:159276503-159277182 (+) GRCh38

MGI Vertebrate Homology

Mptx1 stringent orthology
1 human;1 mouse;1 rat;4 zebrafish
HCOP

vertebrate homology predictions: MPTX1
Gene Tree

Mptx1

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Phenotype Summary

8 phenotype references

All Mutations and Alleles

8
Chemically induced (other)

2
Endonuclease-mediated

3
Targeted

3
Genomic Mutations

2 involving Mptx1
Incidental Mutations

APF
Find Mice (IMSR)

8 strains or lines available

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All GO Annotations

5
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

19

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

22
RefSeq

2
UniProt

2
CCDS

CCDS15541.1

Ensembl

ENSMUSG00000026531 (Evidence)
NCBI Gene

66289

			Length	Strain/Species	Flank
genomic	ENSMUSG00000026531	Ensembl Gene Model \| MGI Sequence Detail	2356	C57BL/6J	± kb
transcript	ENSMUST00000027816	Ensembl \| MGI Sequence Detail	799	Not Applicable
polypeptide	ENSMUSP00000027816	Ensembl \| MGI Sequence Detail	219	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000010918 mucosal pentraxin

(term hierarchy)
InterPro Domains

IPR013320 Concanavalin A-like lectin/glucanase domain superfamily

IPR051005 Pentraxin domain-containing protein

IPR001759 Pentraxin-related
GlyGen

Q8R1M8 1 site

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All nucleic 19

cDNA 19

Microarray probesets 3

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MGI:2138517

Summaries

All 29

Gene Ontology 3

Phenotypes 8
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Mptx1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr10308	Chr1:174158084-174158087 (+)	2 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24