About   Help   FAQ
Art3 Gene Detail
Summary
  • Symbol
    Art3
  • Name
    ADP-ribosyltransferase 3
  • Synonyms
    4930569O04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1202729
    NCBI Gene: 109979
  • Alliance
  • Transcription Start Sites
    20 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:92479686-92562487 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 5, 46.54 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2538 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1202729
protein coding gene Chr5:92479659-92562487 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029749
protein coding gene Chr5:93516050-93612427 (+)
A/J MGP_AJ_G0029715
protein coding gene Chr5:89798195-89889926 (+)
AKR/J MGP_AKRJ_G0029661
protein coding gene Chr5:92737701-92826062 (+)
BALB/cJ MGP_BALBcJ_G0029725
protein coding gene Chr5:90683271-90767632 (+)
C3H/HeJ MGP_C3HHeJ_G0029448
protein coding gene Chr5:93142469-93227175 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030179
protein coding gene Chr5:97225789-97316817 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027415
protein coding gene Chr5:85449488-85533262 (+)
CAST/EiJ MGP_CASTEiJ_G0028858
protein coding gene Chr5:92519276-92608764 (+)
CBA/J MGP_CBAJ_G0029418
protein coding gene Chr5:100601365-100693811 (+)
DBA/2J MGP_DBA2J_G0029562
protein coding gene Chr5:89847029-89930343 (+)
FVB/NJ MGP_FVBNJ_G0029521
protein coding gene Chr5:88691776-88776590 (+)
LP/J MGP_LPJ_G0029650
protein coding gene Chr5:93880798-93972181 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029550
protein coding gene Chr5:105514240-105603311 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030213
protein coding gene Chr5:92266007-92351061 (+)
PWK/PhJ MGP_PWKPhJ_G0028577
protein coding gene Chr5:88911359-88999073 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028412
protein coding gene Chr5:91628839-91716548 (+)
WSB/EiJ MGP_WSBEiJ_G0028937
protein coding gene Chr5:92733012-92823079 (+)



Homology
more
  • Human Ortholog
    ART3, ADP-ribosyltransferase 3 (inactive)
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ART3, ADP-ribosyltransferase 3 (inactive)
  • Synonyms
    ARTC3
  • Links
    NCBI Gene ID: 419
    neXtProt AC: NX_Q13508
    UniProt: Q13508

  • Chr Location
    4p15.1-p14; chr4:76011184-76114048 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034842 Ensembl Gene Model | MGI Sequence Detail 82802 C57BL/6J ±  kb
transcript ENSMUST00000120416 Ensembl | MGI Sequence Detail 1478 Not Applicable  
polypeptide ENSMUSP00000113493 Ensembl | MGI Sequence Detail 408 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 52
    cDNA 50
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1923148
References
more
  • Summaries
    All 42
    Developmental Gene Expression 5
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:331365 Martinez ME, et al., DIO3 protects against thyrotoxicosis-derived cranio-encephalic and cardiac congenital abnormalities. JCI Insight. 2022 Nov 8;7(21)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory