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Reep2 Gene Detail
Summary
  • Symbol
    Reep2
  • Name
    receptor accessory protein 2
  • Synonyms
    MGC:28827
  • Feature Type
    protein coding gene
  • IDs
    MGI:2385070
    NCBI Gene: 225362
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:34973642-34980516 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 18.75 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    218 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2385070
 protein coding gene Chr18:34973642-34980516 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024252
 protein coding gene Chr18:33077323-33084196 (+)
A/J MGP_AJ_G0024218
 protein coding gene Chr18:31957162-31964752 (+)
AKR/J MGP_AKRJ_G0024186
 protein coding gene Chr18:32876411-32883130 (+)
BALB/cJ MGP_BALBcJ_G0024218
 protein coding gene Chr18:32015778-32022651 (+)
C3H/HeJ MGP_C3HHeJ_G0023985
 protein coding gene Chr18:32889501-32896371 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024660
 protein coding gene Chr18:34348418-34355292 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022100
 protein coding gene Chr18:32096878-32103981 (+)
CAST/EiJ MGP_CASTEiJ_G0023460
 protein coding gene Chr18:32853552-32860451 (+)
CBA/J MGP_CBAJ_G0023953
 protein coding gene Chr18:35277616-35286860 (+)
DBA/2J MGP_DBA2J_G0024085
 protein coding gene Chr18:31612266-31618974 (+)
FVB/NJ MGP_FVBNJ_G0024052
 protein coding gene Chr18:31297733-31304607 (+)
LP/J MGP_LPJ_G0024167
 protein coding gene Chr18:33160741-33167614 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024080
 protein coding gene Chr18:36540644-36547514 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024708
 protein coding gene Chr18:32693637-32700511 (+)
PWK/PhJ MGP_PWKPhJ_G0023204
 protein coding gene Chr18:31818278-31825155 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023012
 protein coding gene Chr18:32975597-32982440 (+)
WSB/EiJ MGP_WSBEiJ_G0023523
 protein coding gene Chr18:32626564-32633436 (+)



Homology
more
  • Human Ortholog
    REEP2, receptor accessory protein 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    REEP2, receptor accessory protein 2
  • Synonyms
    C5orf19, SGC32445, SPG72, SPG72A, SPG72B, Yip2d
  • Links
    NCBI Gene ID: 51308
    neXtProt AC: NX_Q9BRK0
    UniProt: Q9BRK0

  • Chr Location
    5q31.2; chr5:138439057-138446969 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human REEP2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    852
  • Tissues
    16
  • cDNA Data
    28
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 225362 NCBI Gene Model | MGI Sequence Detail 6875 C57BL/6J ±  kb
transcript NM_144865 RefSeq | MGI Sequence Detail 1926 C57BL/6  
polypeptide Q8VCD6 UniProt | EBI | MGI Sequence Detail 254 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 28
    cDNA 28

    Microarray probesets 3
Other
Accession IDs
less
MGI:2147414
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:343450 Zhou J, et al., Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development. Hum Mol Genet. 2023 Aug 7;32(16):2587-2599
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory