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Mrpl50 Gene Detail
Summary
  • Symbol
    Mrpl50
  • Name
    mitochondrial ribosomal protein L50
  • Synonyms
    D4Wsu125e
  • Feature Type
    protein coding gene
  • IDs
    MGI:107329
    NCBI Gene: 28028
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:49512597-49521083 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 26.54 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    269 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_107329
 protein coding gene Chr4:49512596-49521093 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028282
 protein coding gene Chr4:47994624-48003126 (-)
A/J MGP_AJ_G0028242
 protein coding gene Chr4:46215530-46224027 (-)
AKR/J MGP_AKRJ_G0028191
 protein coding gene Chr4:47432841-47441338 (-)
BALB/cJ MGP_BALBcJ_G0028261
 protein coding gene Chr4:46324238-46332743 (-)
C3H/HeJ MGP_C3HHeJ_G0027982
 protein coding gene Chr4:47984304-47992801 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028702
 protein coding gene Chr4:49722135-49731865 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026011
 protein coding gene Chr4:43420415-43428818 (-)
CAST/EiJ MGP_CASTEiJ_G0027421
 protein coding gene Chr4:47555917-47565095 (-)
CBA/J MGP_CBAJ_G0027948
 protein coding gene Chr4:51402927-51411424 (-)
DBA/2J MGP_DBA2J_G0028098
 protein coding gene Chr4:46101348-46109853 (-)
FVB/NJ MGP_FVBNJ_G0028065
 protein coding gene Chr4:45365099-45373534 (-)
LP/J MGP_LPJ_G0028197
 protein coding gene Chr4:48072580-48081082 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028089
 protein coding gene Chr4:54339572-54349311 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028737
 protein coding gene Chr4:47626273-47634770 (-)
PWK/PhJ MGP_PWKPhJ_G0027146
 protein coding gene Chr4:46176746-46185528 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026974
 protein coding gene Chr4:47015794-47022456 (-)
WSB/EiJ MGP_WSBEiJ_G0027499
 protein coding gene Chr4:47526685-47541731 (-)



Homology
more
  • Human Ortholog
    MRPL50, mitochondrial ribosomal protein L50
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL50, mitochondrial ribosomal protein L50
  • Synonyms
    mL50, MRP-L50
  • Links
    NCBI Gene ID: 54534
    neXtProt AC: NX_Q8N5N7
    UniProt: Q8N5N7

  • Chr Location
    9q31.1; chr9:101387633-101398618 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    8
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    726
  • Tissues
    13
  • cDNA Data
    84
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 28028 NCBI Gene Model | MGI Sequence Detail 8487 C57BL/6J ±  kb
transcript NM_178603 RefSeq | MGI Sequence Detail 2103 ZRU/MplStud  
polypeptide Q8VDT9 UniProt | EBI | MGI Sequence Detail 159 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 86
    cDNA 84
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGD-MRK-35795, MGI:2140141, MGI:2140233
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 4
  • Earliest
    J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory