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Elac1 Gene Detail
Summary
  • Symbol
    Elac1
  • Name
    elaC ribonuclease Z 1
  • Synonyms
    2610018O07Rik, 8430417G19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1890495
    NCBI Gene: 114615
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:73868109-73887550 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 49.83 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    683 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1890495
 protein coding gene Chr18:73868109-73887589 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024549
 protein coding gene Chr18:74326980-74346417 (-)
A/J MGP_AJ_G0024516
 protein coding gene Chr18:71088234-71107705 (-)
AKR/J MGP_AKRJ_G0024487
 protein coding gene Chr18:73196323-73215764 (-)
BALB/cJ MGP_BALBcJ_G0024516
 protein coding gene Chr18:71263339-71282767 (-)
C3H/HeJ MGP_C3HHeJ_G0024284
 protein coding gene Chr18:73283868-73304019 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024962
 protein coding gene Chr18:76279982-76299418 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022393
 protein coding gene Chr18:70188859-70208482 (-)
CAST/EiJ MGP_CASTEiJ_G0023757
 protein coding gene Chr18:73457311-73477333 (-)
CBA/J MGP_CBAJ_G0024253
 protein coding gene Chr18:78875444-78898447 (-)
DBA/2J MGP_DBA2J_G0024383
 protein coding gene Chr18:70684138-70706496 (-)
FVB/NJ MGP_FVBNJ_G0024349
 protein coding gene Chr18:70024582-70044021 (-)
LP/J MGP_LPJ_G0024467
 protein coding gene Chr18:74201285-74220782 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024379
 protein coding gene Chr18:80362935-80383291 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025010
 protein coding gene Chr18:73321558-73341038 (-)
PWK/PhJ MGP_PWKPhJ_G0023501
 protein coding gene Chr18:71046365-71066831 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023306
 protein coding gene Chr18:73473465-73494122 (-)
WSB/EiJ MGP_WSBEiJ_G0023820
 protein coding gene Chr18:73269727-73290081 (-)



Homology
more
  • Human Ortholog
    ELAC1, elaC ribonuclease Z 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ELAC1, elaC ribonuclease Z 1
  • Synonyms
    D29
  • Links
    NCBI Gene ID: 55520
    neXtProt AC: NX_Q9H777
    UniProt: Q9H777

  • Chr Location
    18q21.2; chr18:50967991-50988121 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Mice homozygous for a transposon insertion are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    24
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000036941 Ensembl Gene Model | MGI Sequence Detail 19442 C57BL/6J ±  kb
transcript ENSMUST00000041138 Ensembl | MGI Sequence Detail 4971 Not Applicable  
polypeptide ENSMUSP00000041793 Ensembl | MGI Sequence Detail 362 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 24

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916451, MGI:1921777
References
more
  • Summaries
    All 33
    Gene Ontology 6
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:237787 Liu X, et al., Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA. BMC Immunol. 2016 Aug 02;17(1):25
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory