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Arl8a Gene Detail
Summary
  • Symbol
    Arl8a
  • Name
    ADP-ribosylation factor-like 8A
  • Synonyms
    1110033P22Rik, Arl10b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915974
    NCBI Gene: 68724
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:135074572-135084007 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 58.24 cM, cytoband F
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    255 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915974
 protein coding gene Chr1:135074562-135084007 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016517
 protein coding gene Chr1:138883595-138894393 (+)
A/J MGP_AJ_G0016500
 protein coding gene Chr1:133639667-133648964 (+)
AKR/J MGP_AKRJ_G0016465
 protein coding gene Chr1:137616996-137626249 (+)
BALB/cJ MGP_BALBcJ_G0016460
 protein coding gene Chr1:133953517-133963292 (+)
C3H/HeJ MGP_C3HHeJ_G0016286
 protein coding gene Chr1:137713531-137724167 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016921
 protein coding gene Chr1:143910325-143921455 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014632
 protein coding gene Chr1:126750964-126760048 (+)
CAST/EiJ MGP_CASTEiJ_G0015866
 protein coding gene Chr1:136785262-136794607 (+)
CBA/J MGP_CBAJ_G0016259
 protein coding gene Chr1:148872610-148888642 (+)
DBA/2J MGP_DBA2J_G0016365
 protein coding gene Chr1:132641338-132651879 (+)
FVB/NJ MGP_FVBNJ_G0016364
 protein coding gene Chr1:131278059-131288967 (+)
LP/J MGP_LPJ_G0016436
 protein coding gene Chr1:140128735-140138155 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016389
 protein coding gene Chr1:154570706-154581134 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016957
 protein coding gene Chr1:137365998-137375171 (+)
PWK/PhJ MGP_PWKPhJ_G0015652
 protein coding gene Chr1:131664488-131674381 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015439
 protein coding gene Chr1:136325489-136336579 (+)
WSB/EiJ MGP_WSBEiJ_G0015929
 protein coding gene Chr1:137394152-137407722 (+)



Homology
more
  • Human Ortholog
    ARL8A, ARF like GTPase 8A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ARL8A, ARF like GTPase 8A
  • Synonyms
    ARL10B, GIE2
  • Links
    NCBI Gene ID: 127829
    neXtProt AC: NX_Q96BM9
    UniProt: Q96BM9

  • Chr Location
    1q32.1; chr1:202133404-202144743 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    784
  • Tissues
    13
  • cDNA Data
    3
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68724 NCBI Gene Model | MGI Sequence Detail 9436 C57BL/6J ±  kb
transcript NM_026823 RefSeq | MGI Sequence Detail 1702 ZRU/MplStud  
polypeptide Q8VEH3 UniProt | EBI | MGI Sequence Detail 186 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000004295 ADP-ribosylation factor-like protein 8A
    (term hierarchy)
  • InterPro Domains
    IPR044154 ADP-ribosylation factor-like protein 8A/8B
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
    IPR006689 Small GTPase superfamily, ARF/SAR type
    IPR005225 Small GTP-binding protein domain
  • GlyGen
    Q8VEH3 1 site, 1 N-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 4
    Genomic 1
    cDNA 3

    Microarray probesets 2
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory