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Cacng5 Gene Detail
Summary
  • Symbol
    Cacng5
  • Name
    calcium channel, voltage-dependent, gamma subunit 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:2157946
    NCBI Gene: 140723
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:107765431-107805881 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 70.44 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1386 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2157946
 protein coding gene Chr11:107765431-107805881 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019324
 protein coding gene Chr11:111310254-111351211 (-)
A/J MGP_AJ_G0019292
 protein coding gene Chr11:106530236-106571226 (-)
AKR/J MGP_AKRJ_G0019261
 protein coding gene Chr11:109716003-109761725 (-)
BALB/cJ MGP_BALBcJ_G0019266
 protein coding gene Chr11:106956013-106996988 (-)
C3H/HeJ MGP_C3HHeJ_G0019075
 protein coding gene Chr11:110029037-110070580 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019716
 protein coding gene Chr11:114733009-114774307 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017340
 protein coding gene Chr11:103789453-103830966 (-)
CAST/EiJ MGP_CASTEiJ_G0018628
 protein coding gene Chr11:111128825-111175330 (-)
CBA/J MGP_CBAJ_G0019044
 protein coding gene Chr11:119472261-119516106 (-)
DBA/2J MGP_DBA2J_G0019156
 protein coding gene Chr11:106010319-106051972 (-)
FVB/NJ MGP_FVBNJ_G0019147
 protein coding gene Chr11:105511869-105558752 (-)
LP/J MGP_LPJ_G0019226
 protein coding gene Chr11:111749076-111792925 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019177
 protein coding gene Chr11:118683867-118725836 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019753
 protein coding gene Chr11:110274019-110316872 (-)
PWK/PhJ MGP_PWKPhJ_G0018393
 protein coding gene Chr11:107156600-107198818 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018184
 protein coding gene Chr11:110030121-110071089 (-)
WSB/EiJ MGP_WSBEiJ_G0018679
 protein coding gene Chr11:110214664-110225360 (-)



Homology
more
  • Human Ortholog
    CACNG5, calcium voltage-gated channel auxiliary subunit gamma 5
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CACNG5, calcium voltage-gated channel auxiliary subunit gamma 5
  • Links
    NCBI Gene ID: 27091
    neXtProt AC: NX_Q9UF02
    UniProt: Q9UF02

  • Chr Location
    17q24.2; chr17:66835117-66894751 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    21
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    857
  • Tissues
    63
  • cDNA Data
    18
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 140723 NCBI Gene Model | MGI Sequence Detail 40451 C57BL/6J ±  kb
transcript NM_001199301 RefSeq | MGI Sequence Detail 3771 C57BL/6  
polypeptide Q8VHW4 UniProt | EBI | MGI Sequence Detail 275 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000004954 voltage-dependent calcium channel gamma-5 subunit
    (term hierarchy)
  • InterPro Domains
    IPR004031 PMP-22/EMP/MP20/Claudin
    IPR008369 Voltage-dependent calcium channel, gamma-5 subunit
    IPR051072 Voltage-dependent calcium channel gamma subunit
    IPR008368 Voltage-dependent calcium channel, gamma subunit
Molecular
Reagents
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  • All nucleic 19
    cDNA 18
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 6
    Gene Ontology 7
    Phenotypes 3
  • Earliest
    J:61749 Burgess DL, et al., Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. Genome Res. 1999 Dec;9(12):1204-13
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory