Imp4 Gene Detail

Summary

• Symbol
  Imp4
• Name
  IMP4, U3 small nucleolar ribonucleoprotein

• Feature Type
  protein coding gene
• IDs
  MGI:106572
  NCBI Gene: 27993
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr1:34478951-34488437 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 1, 13.22 cM
• Mapping Data
  3 experiments

Strain
Comparison

• SNPs within 2kb
  495 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_106572	protein coding gene	Chr1:34478932-34488437 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0015908	protein coding gene	Chr1:32824667-32835124 (+)
A/J	MGP_AJ_G0015892	protein coding gene	Chr1:32042799-32052294 (+)
AKR/J	MGP_AKRJ_G0015848	protein coding gene	Chr1:32428843-32439874 (+)
BALB/cJ	MGP_BALBcJ_G0015846	protein coding gene	Chr1:31691592-31701090 (+)
C3H/HeJ	MGP_C3HHeJ_G0015680	protein coding gene	Chr1:32628359-32637809 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016299	protein coding gene	Chr1:34318415-34329887 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014021	protein coding gene	Chr1:29203181-29212674 (+)
CAST/EiJ	MGP_CASTEiJ_G0015260	protein coding gene	Chr1:32484492-32493923 (+)
CBA/J	MGP_CBAJ_G0015651	protein coding gene	Chr1:35276079-35285585 (+)
DBA/2J	MGP_DBA2J_G0015752	protein coding gene	Chr1:31366468-31376061 (+)
FVB/NJ	MGP_FVBNJ_G0015754	protein coding gene	Chr1:30916064-30925572 (+)
LP/J	MGP_LPJ_G0015822	protein coding gene	Chr1:33166462-33175679 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0015774	protein coding gene	Chr1:37525821-37535308 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016346	protein coding gene	Chr1:32418070-32427554 (+)
PWK/PhJ	MGP_PWKPhJ_G0015043	protein coding gene	Chr1:31097266-31106825 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0014826	protein coding gene	Chr1:32393821-32403226 (+)
WSB/EiJ	MGP_WSBEiJ_G0015322	protein coding gene	Chr1:32402981-32412686 (+)

Homology

• Human Ortholog
  IMP4, IMP U3 small nucleolar ribonucleoprotein 4

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  IMP4, IMP U3 small nucleolar ribonucleoprotein 4
  
• Synonyms
  BXDC4
• Links
  HGNC:30856

  NCBI Gene ID: 92856

  neXtProt AC: NX_Q96G21

  UniProt: Q96G21

  
  
• Chr Location
  2q21.1; chr2:130342877-130347967 (+)  GRCh38

---

• MGI Vertebrate Homology
  Imp4 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: IMP4
• Gene Tree
  Imp4
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotype references
  

• All Mutations and Alleles
  10
• Chemically induced (other)
  1
• Gene trapped
  8
• Targeted
  1
• Genomic Mutations
  1 involving Imp4
• Incidental Mutations
  CvDC
• Find Mice (IMSR)
  22 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  17
• GO References
  7

Expression

• Assay Results
  734
• Tissues
  6
• cDNA Data
  118
• Literature Summary
  2

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase imp4

Sequences &
Gene Models

• All Sequences
  59
• RefSeq
  4
• UniProt
  3
• CCDS
  CCDS35536.1

• Ensembl
  ENSMUSG00000026127 (Evidence)
• NCBI Gene
  27993

Representative Sequences			Length	Strain/Species
genomic	27993	NCBI Gene Model | MGI Sequence Detail	9487	C57BL/6J
transcript	NM_001420705	RefSeq | MGI Sequence Detail	5928	ZRU/MplStud
polypeptide	Q8VHZ7	UniProt | EBI | MGI Sequence Detail	291	Not Applicable

Protein
Information

• UniProt
  3 Sequences
• Protein Ontology
  PR:000009016 U3 small nucleolar ribonucleoprotein protein IMP4
  (term hierarchy)
• InterPro Domains
  IPR007109 Brix domain
  IPR044281 U3 snoRNP protein/Ribosome production factor 1

Molecular
Reagents

• All nucleic 119

  cDNA 118

  Primer pair 1

  
  

  Microarray probesets 5

Other
Accession IDs

MGD-MRK-34266, MGI:2138091, MGI:2138515

References

• Summaries
  All 36

  Developmental Gene Expression 2

  Gene Ontology 7

  Phenotypes 7
• Earliest
  J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Imp4:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr6215	Chr1:34478936-34478991 (+)	13 bp