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Depdc7 Gene Detail
Summary
  • Symbol
    Depdc7
  • Name
    DEP domain containing 7
  • Synonyms
    MGC:19163
  • Feature Type
    protein coding gene
  • IDs
    MGI:2139258
    NCBI Gene: 211896
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:104552129-104573202 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 54.91 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    589 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2139258
 protein coding gene Chr2:104552129-104573223 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026221
 protein coding gene Chr2:106836681-106859545 (-)
A/J MGP_AJ_G0026182
 protein coding gene Chr2:102379946-102402019 (-)
AKR/J MGP_AKRJ_G0026162
 protein coding gene Chr2:105169978-105192867 (-)
BALB/cJ MGP_BALBcJ_G0026191
 protein coding gene Chr2:102663231-102684872 (-)
C3H/HeJ MGP_C3HHeJ_G0025942
 protein coding gene Chr2:105497091-105518258 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026642
 protein coding gene Chr2:110354159-110386625 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024029
 protein coding gene Chr2:98195535-98216937 (-)
CAST/EiJ MGP_CASTEiJ_G0025406
 protein coding gene Chr2:106004609-106027591 (-)
CBA/J MGP_CBAJ_G0025919
 protein coding gene Chr2:114137378-114164239 (-)
DBA/2J MGP_DBA2J_G0026057
 protein coding gene Chr2:101929720-101951415 (-)
FVB/NJ MGP_FVBNJ_G0026020
 protein coding gene Chr2:100911072-100932126 (-)
LP/J MGP_LPJ_G0026160
 protein coding gene Chr2:106953179-106976771 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026044
 protein coding gene Chr2:118002060-118025308 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026696
 protein coding gene Chr2:105373373-105394261 (-)
PWK/PhJ MGP_PWKPhJ_G0025141
 protein coding gene Chr2:101465316-101487072 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024942
 protein coding gene Chr2:104597873-104621558 (-)
WSB/EiJ MGP_WSBEiJ_G0025473
 protein coding gene Chr2:106101985-106124785 (-)



Homology
more
  • Human Ortholog
    DEPDC7, DEP domain containing 7
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DEPDC7, DEP domain containing 7
  • Synonyms
    dJ85M6.4, TR2
  • Links
    NCBI Gene ID: 91614
    neXtProt AC: NX_Q96QD5
    UniProt: Q96QD5

  • Chr Location
    11p13; chr11:33015876-33033582 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    15
  • cDNA Data
    41
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 211896 NCBI Gene Model | MGI Sequence Detail 21074 C57BL/6J ±  kb
transcript NM_144804 RefSeq | MGI Sequence Detail 1780 C57BL/6  
polypeptide Q91WS7 UniProt | EBI | MGI Sequence Detail 511 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 41
    cDNA 41

    Microarray probesets 4
References
more
  • Summaries
    All 39
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory