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Smarcd2 Gene Detail
Summary
  • Symbol
    Smarcd2
  • Name
    SWI/SNF related BAF chromatin remodeling complex subunit D2
  • Synonyms
    Baf60b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1933621
    NCBI Gene: 83796
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:106154005-106163798 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 68.89 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    222 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1933621
 protein coding gene Chr11:106153997-106163810 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019301
 protein coding gene Chr11:109553264-109563012 (-)
A/J MGP_AJ_G0019269
 protein coding gene Chr11:104890085-104899827 (-)
AKR/J MGP_AKRJ_G0019238
 protein coding gene Chr11:108017385-108027198 (-)
BALB/cJ MGP_BALBcJ_G0019243
 protein coding gene Chr11:105298373-105308569 (-)
C3H/HeJ MGP_C3HHeJ_G0019052
 protein coding gene Chr11:108306939-108316731 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019693
 protein coding gene Chr11:112902708-112912536 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017317
 protein coding gene Chr11:102167746-102177173 (-)
CAST/EiJ MGP_CASTEiJ_G0018605
 protein coding gene Chr11:109362618-109372698 (-)
CBA/J MGP_CBAJ_G0019021
 protein coding gene Chr11:117602836-117612632 (-)
DBA/2J MGP_DBA2J_G0019133
 protein coding gene Chr11:104358066-104367863 (-)
FVB/NJ MGP_FVBNJ_G0019124
 protein coding gene Chr11:103861754-103871783 (-)
LP/J MGP_LPJ_G0019203
 protein coding gene Chr11:109994215-110006768 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019154
 protein coding gene Chr11:116886922-116896716 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019730
 protein coding gene Chr11:108510438-108521444 (-)
PWK/PhJ MGP_PWKPhJ_G0018370
 protein coding gene Chr11:105455152-105465429 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018161
 protein coding gene Chr11:108272834-108282375 (-)
WSB/EiJ MGP_WSBEiJ_G0018656
 protein coding gene Chr11:108472384-108482559 (-)



Homology
more
  • Human Ortholog
    SMARCD2, SWI/SNF related BAF chromatin remodeling complex subunit D2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SMARCD2, SWI/SNF related BAF chromatin remodeling complex subunit D2
  • Synonyms
    BAF60B, CRACD2, PRO2451, Rsc6p, SGD2
  • Links
    NCBI Gene ID: 6603
    neXtProt AC: NX_Q92925
    UniProt: Q92925

  • Chr Location
    17q23.3; chr17:63832081-63843065 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    22
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    929
  • Tissues
    116
  • cDNA Data
    211
  • Literature Summary
    21
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000078619 Ensembl Gene Model | MGI Sequence Detail 9794 C57BL/6J ±  kb
    transcript ENSMUST00000021052 Ensembl | MGI Sequence Detail 2747 Not Applicable  
    polypeptide ENSMUSP00000021052 Ensembl | MGI Sequence Detail 531 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      4 Sequences
    • Protein Ontology
      PR:000015266 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
      (term hierarchy)
    • InterPro Domains
      IPR019835 SWIB domain
      IPR003121 SWIB/MDM2 domain
      IPR036885 SWIB/MDM2 domain superfamily
      IPR030090 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D 2, SWIB domain
    • GlyGen
      Q99JR8 1 site, 1 O-linked glycan (1 site)
    Molecular
    Reagents
    less
    • All nucleic 214
      cDNA 211
      Primer pair 3

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2144524
    References
    more
    • Summaries
      All 67
      Developmental Gene Expression 21
      Gene Ontology 22
      Phenotypes 10
    • Earliest
      J:35263 Wang W, et al., Diversity and specialization of mammalian SWI/SNF complexes. Genes Dev. 1996 Sep 1;10(17):2117-30
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory