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Higd1b Gene Detail
Summary
  • Symbol
    Higd1b
  • Name
    HIG1 domain family, member 1B
  • Synonyms
    2310056K19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922939
    NCBI Gene: 75689
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:102726675-102728866 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 66.48 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    149 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922939
 protein coding gene Chr11:102726597-102728866 (+)
129S1/SvImJ MGP_129S1SvImJ_G0019245
 protein coding gene Chr11:105866938-105869129 (+)
A/J MGP_AJ_G0019213
 protein coding gene Chr11:101380842-101383033 (+)
AKR/J MGP_AKRJ_G0019182
 protein coding gene Chr11:104512967-104515158 (+)
BALB/cJ MGP_BALBcJ_G0019187
 protein coding gene Chr11:101856593-101858784 (+)
C3H/HeJ MGP_C3HHeJ_G0018996
 protein coding gene Chr11:104727899-104730090 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019636
 protein coding gene Chr11:109143739-109145930 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0017262
 protein coding gene Chr11:98804875-98807084 (+)
CAST/EiJ MGP_CASTEiJ_G0018550
 protein coding gene Chr11:105737909-105740101 (+)
CBA/J MGP_CBAJ_G0018965
 protein coding gene Chr11:113659835-113662026 (+)
DBA/2J MGP_DBA2J_G0019077
 protein coding gene Chr11:100892265-100894456 (+)
FVB/NJ MGP_FVBNJ_G0019067
 protein coding gene Chr11:100432364-100434555 (+)
LP/J MGP_LPJ_G0019146
 protein coding gene Chr11:106381721-106383912 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019098
 protein coding gene Chr11:113116478-113118669 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019674
 protein coding gene Chr11:104893167-104895358 (+)
PWK/PhJ MGP_PWKPhJ_G0018313
 protein coding gene Chr11:101963801-101965995 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018105
 protein coding gene Chr11:104658310-104660498 (+)
WSB/EiJ MGP_WSBEiJ_G0018599
 protein coding gene Chr11:104886128-104888319 (+)



Homology
more
  • Human Ortholog
    HIGD1B, HIG1 hypoxia inducible domain family member 1B
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HIGD1B, HIG1 hypoxia inducible domain family member 1B
  • Synonyms
    CLST11240, CLST11240-15
  • Links
    NCBI Gene ID: 51751
    neXtProt AC: NX_Q9P298
    UniProt: Q9P298

  • Chr Location
    17q21.31; chr17:44844860-44850476 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020928 Ensembl Gene Model | MGI Sequence Detail 2192 C57BL/6J ±  kb
transcript ENSMUST00000107072 Ensembl | MGI Sequence Detail 497 Not Applicable  
polypeptide ENSMUSP00000102687 Ensembl | MGI Sequence Detail 98 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Gene Ontology 2
    Phenotypes 10
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:174216 Terzian T, et al., Rpl27a mutation in the sooty foot ataxia mouse phenocopies high p53 mouse models. J Pathol. 2011 Aug;224(4):540-52
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory