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Fuca2 Gene Detail
Summary
  • Symbol
    Fuca2
  • Name
    fucosidase, alpha-L- 2, plasma
  • Synonyms
    0610025O11Rik, 5530401P20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914098
    NCBI Gene: 66848
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:13376314-13394779 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 4.86 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    656 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914098
 protein coding gene Chr10:13375284-13394779 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017022
 protein coding gene Chr10:10911666-10931974 (+)
A/J MGP_AJ_G0017000
 protein coding gene Chr10:10502866-10523242 (+)
AKR/J MGP_AKRJ_G0016964
 protein coding gene Chr10:10746875-10767183 (+)
BALB/cJ MGP_BALBcJ_G0016958
 protein coding gene Chr10:10522911-10543267 (+)
C3H/HeJ MGP_C3HHeJ_G0016783
 protein coding gene Chr10:10899778-10920156 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017420
 protein coding gene Chr10:11203405-11223007 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015125
 protein coding gene Chr10:9777422-9798179 (+)
CAST/EiJ MGP_CASTEiJ_G0016365
 protein coding gene Chr10:10773176-10793335 (+)
CBA/J MGP_CBAJ_G0016755
 protein coding gene Chr10:11636828-11659648 (+)
DBA/2J MGP_DBA2J_G0016863
 protein coding gene Chr10:10413548-10433642 (+)
FVB/NJ MGP_FVBNJ_G0016858
 protein coding gene Chr10:10243178-10263548 (+)
LP/J MGP_LPJ_G0016938
 protein coding gene Chr10:10768033-10788399 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016888
 protein coding gene Chr10:11517874-11538163 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017458
 protein coding gene Chr10:10632503-10652879 (+)
PWK/PhJ MGP_PWKPhJ_G0016150
 protein coding gene Chr10:10294274-10314571 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015933
 protein coding gene Chr10:10779783-10801823 (+)
WSB/EiJ MGP_WSBEiJ_G0016427
 protein coding gene Chr10:10674338-10694655 (+)



Homology
more
  • Human Ortholog
    FUCA2, alpha-L-fucosidase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FUCA2, alpha-L-fucosidase 2
  • Synonyms
    dJ20N2.5
  • Links
    NCBI Gene ID: 2519
    neXtProt AC: NX_Q9BTY2
    UniProt: Q9BTY2

  • Chr Location
    6q24.2; chr6:143494812-143511720 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
No notable phenotype was detected in a high-throughput screen of homozygous mutant mice.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    824
  • Tissues
    98
  • cDNA Data
    18
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66848 NCBI Gene Model | MGI Sequence Detail 18466 C57BL/6J ±  kb
transcript NM_025799 RefSeq | MGI Sequence Detail 5656 C57BL/6  
polypeptide Q99KR8 UniProt | EBI | MGI Sequence Detail 461 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 4
Other
Accession IDs
less
MGI:1922991
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:196085 Phopin K, et al., Roles of mouse sperm-associated alpha-L-fucosidases in fertilization. Mol Reprod Dev. 2013 Apr;80(4):273-85
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory