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Mlf2 Gene Detail
Summary
  • Symbol
    Mlf2
  • Name
    myeloid leukemia factor 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1353554
    NCBI Gene: 30853
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:124908351-124913112 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 59.17 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    160 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1353554
 protein coding gene Chr6:124908349-124914201 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031278
 protein coding gene Chr6:128249262-128255092 (+)
A/J MGP_AJ_G0031248
 protein coding gene Chr6:123419295-123425157 (+)
AKR/J MGP_AKRJ_G0031176
 protein coding gene Chr6:126789761-126795612 (+)
BALB/cJ MGP_BALBcJ_G0031256
 protein coding gene Chr6:123017963-123023844 (+)
C3H/HeJ MGP_C3HHeJ_G0030979
 protein coding gene Chr6:126837425-126843301 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031712
 protein coding gene Chr6:131632722-131638595 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028862
 protein coding gene Chr6:120627708-120633592 (+)
CAST/EiJ MGP_CASTEiJ_G0030360
 protein coding gene Chr6:127048360-127056241 (+)
CBA/J MGP_CBAJ_G0030940
 protein coding gene Chr6:136666281-136672138 (+)
DBA/2J MGP_DBA2J_G0031096
 protein coding gene Chr6:122347352-122353243 (+)
FVB/NJ MGP_FVBNJ_G0031046
 protein coding gene Chr6:121251081-121256914 (+)
LP/J MGP_LPJ_G0031176
 protein coding gene Chr6:128417206-128424603 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031084
 protein coding gene Chr6:140715692-140721520 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031747
 protein coding gene Chr6:126681248-126687087 (+)
PWK/PhJ MGP_PWKPhJ_G0030075
 protein coding gene Chr6:120582946-120586800 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029904
 protein coding gene Chr6:124762838-124768602 (+)
WSB/EiJ MGP_WSBEiJ_G0030445
 protein coding gene Chr6:127046571-127052408 (+)



Homology
more
  • Human Ortholog
    MLF2, myeloid leukemia factor 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MLF2, myeloid leukemia factor 2
  • Synonyms
    NTN4
  • Links
    NCBI Gene ID: 8079
    neXtProt AC: NX_Q15773
    UniProt: Q15773

  • Chr Location
    12p13.31; chr12:6747996-6767475 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    12
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 30853 NCBI Gene Model | MGI Sequence Detail 4762 C57BL/6J ±  kb
transcript NM_145385 RefSeq | MGI Sequence Detail 1551 C57BL/6  
polypeptide Q99KX1 UniProt | EBI | MGI Sequence Detail 247 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 3
Other
Accession IDs
less
MGI:1889801, MGI:2141560
References
more
  • Summaries
    All 35
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:346416 Koopmans F, et al., SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse. Neuron. 2019 Jul 17;103(2):217-234.e4
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory