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Dhrs1 Gene Detail
Summary
  • Symbol
    Dhrs1
  • Name
    dehydrogenase/reductase 1
  • Synonyms
    1110029G07Rik, dehydrogenase/reductase (SDR family) member 1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1196314
    NCBI Gene: 52585
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:55976477-55983147 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 28.19 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    207 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1196314
 protein coding gene Chr14:55976477-55983147 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021366
 protein coding gene Chr14:49781480-49788150 (-)
A/J MGP_AJ_G0021325
 protein coding gene Chr14:48792801-48799470 (-)
AKR/J MGP_AKRJ_G0021301
 protein coding gene Chr14:50543408-50550077 (-)
BALB/cJ MGP_BALBcJ_G0021329
 protein coding gene Chr14:48758507-48765176 (-)
C3H/HeJ MGP_C3HHeJ_G0021109
 protein coding gene Chr14:50224768-50231437 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021767
 protein coding gene Chr14:52275018-52281694 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019314
 protein coding gene Chr14:47162372-47168984 (-)
CAST/EiJ MGP_CASTEiJ_G0020628
 protein coding gene Chr14:46492061-46498777 (-)
CBA/J MGP_CBAJ_G0021076
 protein coding gene Chr14:53842310-53848982 (-)
DBA/2J MGP_DBA2J_G0021197
 protein coding gene Chr14:48512336-48519006 (-)
FVB/NJ MGP_FVBNJ_G0021179
 protein coding gene Chr14:47959706-47966375 (-)
LP/J MGP_LPJ_G0021271
 protein coding gene Chr14:50829770-50836444 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021203
 protein coding gene Chr14:53197536-53204206 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021794
 protein coding gene Chr14:49724763-49731433 (-)
PWK/PhJ MGP_PWKPhJ_G0020375
 protein coding gene Chr14:45046180-45052917 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020203
 protein coding gene Chr14:45732503-45738991 (-)
WSB/EiJ MGP_WSBEiJ_G0020681
 protein coding gene Chr14:50010120-50016815 (-)



Homology
more
  • Human Ortholog
    DHRS1, dehydrogenase/reductase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DHRS1, dehydrogenase/reductase 1
  • Synonyms
    SDR19C1
  • Links
    NCBI Gene ID: 115817
    neXtProt AC: NX_Q96LJ7
    UniProt: Q96LJ7

  • Chr Location
    14q12; chr14:24290598-24299780 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    725
  • Tissues
    3
  • cDNA Data
    115
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 52585 NCBI Gene Model | MGI Sequence Detail 6671 C57BL/6J ±  kb
transcript NM_026819 RefSeq | MGI Sequence Detail 1486 ZRU/MplStud  
polypeptide Q99L04 UniProt | EBI | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 116
    cDNA 115
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1915960, MGI:2145801
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory