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Abcf2 Gene Detail
Summary
  • Symbol
    Abcf2
  • Name
    ATP-binding cassette, sub-family F member 2
  • Synonyms
    0710005O05Rik, Drr3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1351657
    NCBI Gene: 27407
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:24770343-24782465 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 11.93 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    256 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1351657
 protein coding gene Chr5:24770339-24782465 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029350
 protein coding gene Chr5:22311659-22323766 (-)
A/J MGP_AJ_G0029316
 protein coding gene Chr5:21540489-21552606 (-)
AKR/J MGP_AKRJ_G0029267
 protein coding gene Chr5:22404024-22415987 (-)
BALB/cJ MGP_BALBcJ_G0029327
 protein coding gene Chr5:22055396-22067514 (-)
C3H/HeJ MGP_C3HHeJ_G0029047
 protein coding gene Chr5:22524679-22536648 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029780
 protein coding gene Chr5:23806757-23822817 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027018
 protein coding gene Chr5:19481094-19493385 (-)
CAST/EiJ MGP_CASTEiJ_G0028459
 protein coding gene Chr5:21701863-21714681 (-)
CBA/J MGP_CBAJ_G0029014
 protein coding gene Chr5:24191431-24207547 (-)
DBA/2J MGP_DBA2J_G0029165
 protein coding gene Chr5:21832720-21845576 (-)
FVB/NJ MGP_FVBNJ_G0029123
 protein coding gene Chr5:21207857-21220495 (-)
LP/J MGP_LPJ_G0029249
 protein coding gene Chr5:22708598-22720857 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029152
 protein coding gene Chr5:25306404-25323450 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029814
 protein coding gene Chr5:22056958-22072036 (-)
PWK/PhJ MGP_PWKPhJ_G0028183
 protein coding gene Chr5:20914848-20927334 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028014
 protein coding gene Chr5:21403345-21417297 (-)
WSB/EiJ MGP_WSBEiJ_G0028539
 protein coding gene Chr5:22126298-22140071 (-)



Homology
more
  • Human Ortholog
    ABCF2, ATP binding cassette subfamily F member 2
  • Vertebrate Orthologs
    5
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ABCF2, ATP binding cassette subfamily F member 2
  • Synonyms
    ABC28, EST133090, HUSSY-18, HUSSY18
  • Links
    NCBI Gene ID: 10061
    neXtProt AC: NX_Q9UG63
    UniProt: Q9UG63

  • Chr Location
    7q36.1; chr7:151211484-151227205 (-)  GRCh38
  • Human Ortholog
    ABCF2-H2BK1, ABCF2-H2BK1 readthrough
  • Synonyms
    ABCF2-H2BE1
  • Links
    NCBI Gene ID: 114483834
    neXtProt AC: NX_Q9UG63

  • Chr Location
    chr7:151207837-151227205 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    819
  • Tissues
    108
  • cDNA Data
    152
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028953 Ensembl Gene Model | MGI Sequence Detail 12123 C57BL/6J ±  kb
transcript ENSMUST00000030795 Ensembl | MGI Sequence Detail 2569 Not Applicable  
polypeptide ENSMUSP00000030795 Ensembl | MGI Sequence Detail 628 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000029256 ATP-binding cassette sub-family F member 2
    (term hierarchy)
  • InterPro Domains
    IPR003593 AAA+ ATPase domain
    IPR032781 ABC-transporter extension domain
    IPR003439 ABC transporter-like, ATP-binding domain
    IPR017871 ABC transporter-like, conserved site
    IPR050611 ATP-binding cassette sub-family F member, EF3 subfamily
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
  • GlyGen
    Q99LE6 2 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 154
    cDNA 153
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1298380, MGI:1924146
References
more
  • Summaries
    All 53
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 5
    Phenotypes 16
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:313842 Mattebo A, et al., Yippee like 4 (Ypel4) is essential for normal mouse red blood cell membrane integrity. Sci Rep. 2021 Aug 5;11(1):15898
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory