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Tmed6 Gene Detail
Summary
  • Symbol
    Tmed6
  • Name
    transmembrane p24 trafficking protein 6
  • Synonyms
    1810015P03Rik, 1810018I24Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913519
    NCBI Gene: 66269
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:107788116-107792276 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.58 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913519
 protein coding gene Chr8:107788108-107792276 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034096
 protein coding gene Chr8:109476520-109480709 (-)
A/J MGP_AJ_G0034076
 protein coding gene Chr8:105084879-105091748 (-)
AKR/J MGP_AKRJ_G0034002
 protein coding gene Chr8:108151300-108157004 (-)
BALB/cJ MGP_BALBcJ_G0034069
 protein coding gene Chr8:105284624-105288750 (-)
C3H/HeJ MGP_C3HHeJ_G0033781
 protein coding gene Chr8:108875502-108879666 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034589
 protein coding gene Chr8:113468191-113472278 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031531
 protein coding gene Chr8:98189367-98193483 (-)
CAST/EiJ MGP_CASTEiJ_G0033108
 protein coding gene Chr8:108400448-108404478 (-)
CBA/J MGP_CBAJ_G0033754
 protein coding gene Chr8:117150640-117154769 (-)
DBA/2J MGP_DBA2J_G0033909
 protein coding gene Chr8:104414129-104419003 (-)
FVB/NJ MGP_FVBNJ_G0033854
 protein coding gene Chr8:103355054-103359169 (-)
LP/J MGP_LPJ_G0034000
 protein coding gene Chr8:109657136-109662827 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0033899
 protein coding gene Chr8:120262244-120266318 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034607
 protein coding gene Chr8:108079148-108083291 (-)
PWK/PhJ MGP_PWKPhJ_G0032809
 protein coding gene Chr8:103835652-103840204 (-)
SPRET/EiJ MGP_SPRETEiJ_G0032649
 protein coding gene Chr8:106792704-106798807 (-)
WSB/EiJ MGP_WSBEiJ_G0033223
 protein coding gene Chr8:108799930-108805795 (-)



Homology
more
  • Human Ortholog
    TMED6, transmembrane p24 trafficking protein 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMED6, transmembrane p24 trafficking protein 6
  • Synonyms
    p24g5, PRO34237, SPLL9146
  • Links
    NCBI Gene ID: 146456
    neXtProt AC: NX_Q8WW62
    UniProt: Q8WW62

  • Chr Location
    16q22.1; chr16:69343250-69351786 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    19
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66269 NCBI Gene Model | MGI Sequence Detail 4161 C57BL/6J ±  kb
    transcript NM_025458 RefSeq | MGI Sequence Detail 863 C57BL/6  
    polypeptide Q9CQG0 UniProt | EBI | MGI Sequence Detail 239 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 20
      cDNA 20

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1925557
    References
    more
    • Summaries
      All 26
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 3
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory