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Smim8 Gene Detail
Summary
  • Symbol
    Smim8
  • Name
    small integral membrane protein 8
  • Synonyms
    1810030N24Rik, 2810406B13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913541
    NCBI Gene: 66291
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:34768664-34778398 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 16.86 cM, cytoband A5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    411 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913541
 protein coding gene Chr4:34768664-34778423 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028132
 protein coding gene Chr4:32363703-32373459 (-)
A/J MGP_AJ_G0028090
 protein coding gene Chr4:31196903-31206736 (-)
AKR/J MGP_AKRJ_G0028053
 protein coding gene Chr4:32011842-32021657 (-)
BALB/cJ MGP_BALBcJ_G0028101
 protein coding gene Chr4:31465449-31475208 (-)
C3H/HeJ MGP_C3HHeJ_G0027830
 protein coding gene Chr4:32323478-32333426 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028543
 protein coding gene Chr4:33595675-33605454 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025884
 protein coding gene Chr4:29293038-29303078 (-)
CAST/EiJ MGP_CASTEiJ_G0027285
 protein coding gene Chr4:32120480-32133729 (-)
CBA/J MGP_CBAJ_G0027802
 protein coding gene Chr4:34691223-34701038 (-)
DBA/2J MGP_DBA2J_G0027946
 protein coding gene Chr4:31167496-31177833 (-)
FVB/NJ MGP_FVBNJ_G0027912
 protein coding gene Chr4:30583851-30594035 (-)
LP/J MGP_LPJ_G0028054
 protein coding gene Chr4:32450724-32460482 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027945
 protein coding gene Chr4:37288514-37299178 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028602
 protein coding gene Chr4:32035796-32045534 (-)
PWK/PhJ MGP_PWKPhJ_G0027004
 protein coding gene Chr4:31195763-31205447 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026833
 protein coding gene Chr4:31901285-31912260 (-)
WSB/EiJ MGP_WSBEiJ_G0027361
 protein coding gene Chr4:32032038-32043484 (-)



Homology
more
  • Human Ortholog
    SMIM8, small integral membrane protein 8
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SMIM8, small integral membrane protein 8
  • Synonyms
    C6orf162, dJ102H19.2
  • Links
    NCBI Gene ID: 57150
    neXtProt AC: NX_Q96KF7
    UniProt: Q96KF7

  • Chr Location
    6q15; chr6:87322583-87399749 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Males homozygous for a null allele show normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    781
  • Tissues
    38
  • cDNA Data
    43
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66291 NCBI Gene Model | MGI Sequence Detail 9735 C57BL/6J ±  kb
    transcript NM_025471 RefSeq | MGI Sequence Detail 974 C57BL/6  
    polypeptide Q9CQQ0 UniProt | EBI | MGI Sequence Detail 97 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 43
      cDNA 43

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:1917441
    References
    more
    • Summaries
      All 35
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/22/2024
    MGI 6.24     		The Jackson Laboratory