About   Help   FAQ
Retreg3 Gene Detail
Summary
  • Symbol
    Retreg3
  • Name
    reticulophagy regulator family member 3
  • Synonyms
    1300010M03Rik, 4933404C01Rik, Fam134c
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915248
    NCBI Gene: 67998
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:100987148-101010719 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 64.20 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    484 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915248
 protein coding gene Chr11:100987148-101010720 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019181
 protein coding gene Chr11:103907144-103934312 (-)
A/J MGP_AJ_G0019149
 protein coding gene Chr11:99553600-99578286 (-)
AKR/J MGP_AKRJ_G0019118
 protein coding gene Chr11:102650633-102675203 (-)
BALB/cJ MGP_BALBcJ_G0019123
 protein coding gene Chr11:100048108-100071448 (-)
C3H/HeJ MGP_C3HHeJ_G0018932
 protein coding gene Chr11:102820555-102844070 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019572
 protein coding gene Chr11:107122263-107157494 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017198
 protein coding gene Chr11:96971983-96996635 (-)
CAST/EiJ MGP_CASTEiJ_G0018486
 protein coding gene Chr11:103808870-103834086 (-)
CBA/J MGP_CBAJ_G0018901
 protein coding gene Chr11:111586100-111616352 (-)
DBA/2J MGP_DBA2J_G0019013
 protein coding gene Chr11:99088613-99111936 (-)
FVB/NJ MGP_FVBNJ_G0019003
 protein coding gene Chr11:98631958-98655425 (-)
LP/J MGP_LPJ_G0019082
 protein coding gene Chr11:104457003-104481453 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019034
 protein coding gene Chr11:111154640-111179439 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019610
 protein coding gene Chr11:102970175-102993585 (-)
PWK/PhJ MGP_PWKPhJ_G0018249
 protein coding gene Chr11:100139451-100163290 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018041
 protein coding gene Chr11:102705284-102733343 (-)
WSB/EiJ MGP_WSBEiJ_G0018535
 protein coding gene Chr11:102968543-102996114 (-)



Homology
more
  • Human Ortholog
    RETREG3, reticulophagy regulator family member 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RETREG3, reticulophagy regulator family member 3
  • Synonyms
    FAM134C
  • Links
    NCBI Gene ID: 162427
    neXtProt AC: NX_Q86VR2
    UniProt: Q86VR2

  • Chr Location
    17q21.2; chr17:42579508-42610623 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotypes from 2 alleles in 2 genetic backgrounds
    17 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    34
  • cDNA Data
    15
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000017802 Ensembl Gene Model | MGI Sequence Detail 23572 C57BL/6J ±  kb
    transcript ENSMUST00000017946 Ensembl | MGI Sequence Detail 3165 Not Applicable  
    polypeptide ENSMUSP00000017946 Ensembl | MGI Sequence Detail 466 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 15

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1921678, MGI:2144219, MGI:5897462
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 2
      Gene Ontology 5
      Phenotypes 17
    • Earliest
      J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
    • Latest
      J:354136 Iavarone F, et al., Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo. EMBO Rep. 2024 Jul 22;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory