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Ufc1 Gene Detail
Summary
  • Symbol
    Ufc1
  • Name
    ubiquitin-fold modifier conjugating enzyme 1
  • Synonyms
    1110021H02Rik, ESTM29
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913405
    NCBI Gene: 66155
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:171116137-171122575 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 79.31 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    236 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913405
 protein coding gene Chr1:171116136-171122597 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016754
 protein coding gene Chr1:177075750-177082248 (-)
A/J MGP_AJ_G0016734
 protein coding gene Chr1:169869419-169875760 (-)
AKR/J MGP_AKRJ_G0016700
 protein coding gene Chr1:174959546-174965920 (-)
BALB/cJ MGP_BALBcJ_G0016695
 protein coding gene Chr1:170359677-170366596 (-)
C3H/HeJ MGP_C3HHeJ_G0016518
 protein coding gene Chr1:175202644-175209644 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017156
 protein coding gene Chr1:182961934-182968643 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014864
 protein coding gene Chr1:161550474-161556832 (-)
CAST/EiJ MGP_CASTEiJ_G0016099
 protein coding gene Chr1:174832966-174839905 (-)
CBA/J MGP_CBAJ_G0016493
 protein coding gene Chr1:189474571-189484391 (-)
DBA/2J MGP_DBA2J_G0016600
 protein coding gene Chr1:168709666-168715872 (-)
FVB/NJ MGP_FVBNJ_G0016596
 protein coding gene Chr1:167057148-167063566 (-)
LP/J MGP_LPJ_G0016671
 protein coding gene Chr1:178195325-178203024 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016623
 protein coding gene Chr1:196758095-196765240 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017193
 protein coding gene Chr1:174828687-174835031 (-)
PWK/PhJ MGP_PWKPhJ_G0015885
 protein coding gene Chr1:167934160-167940636 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015669
 protein coding gene Chr1:173613748-173620054 (-)
WSB/EiJ MGP_WSBEiJ_G0016161
 protein coding gene Chr1:174944971-174952399 (-)



Homology
more
  • Human Ortholog
    UFC1, ubiquitin-fold modifier conjugating enzyme 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UFC1, ubiquitin-fold modifier conjugating enzyme 1
  • Synonyms
    HSPC155, NEDSG
  • Links
    NCBI Gene ID: 51506
    neXtProt AC: NX_Q9Y3C8
    UniProt: Q9Y3C8

  • Chr Location
    1q23.3; chr1:161152776-161158856 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human UFC1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    723
  • Tissues
    3
  • cDNA Data
    118
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66155 NCBI Gene Model | MGI Sequence Detail 6439 C57BL/6J ±  kb
transcript NM_001360933 RefSeq | MGI Sequence Detail 1013 ZRU/MplStud  
polypeptide Q9CR09 UniProt | EBI | MGI Sequence Detail 167 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 121
    Genomic 2
    cDNA 118
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1334423
References
more
  • Summaries
    All 37
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:52606 Eddleston J, et al., Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). Genomics. 1999 Mar 1;56(2):149-59
  • Latest
    J:300137 Balce DR, et al., UFMylation inhibits the proinflammatory capacity of interferon-gamma-activated macrophages. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2011763118
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory