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Vta1 Gene Detail
Summary
  • Symbol
    Vta1
  • Name
    vesicle (multivesicular body) trafficking 1
  • Synonyms
    1110001D18Rik, 1110059P08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913451
    NCBI Gene: 66201
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:14531077-14581233 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 10, 5.50 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1182 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913451
protein coding gene Chr10:14530499-14581304 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017028
protein coding gene Chr10:12146046-12204027 (-)
A/J MGP_AJ_G0017006
protein coding gene Chr10:11664159-11722692 (-)
AKR/J MGP_AKRJ_G0016970
protein coding gene Chr10:11923484-11973924 (-)
BALB/cJ MGP_BALBcJ_G0016964
protein coding gene Chr10:11693194-11749500 (-)
C3H/HeJ MGP_C3HHeJ_G0016789
protein coding gene Chr10:12110190-12166570 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017426
protein coding gene Chr10:12440060-12495527 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015131
protein coding gene Chr10:10892174-10944816 (-)
CAST/EiJ MGP_CASTEiJ_G0016371
protein coding gene Chr10:11984033-12039711 (-)
CBA/J MGP_CBAJ_G0016761
protein coding gene Chr10:12924065-12984550 (-)
DBA/2J MGP_DBA2J_G0016869
protein coding gene Chr10:11603840-11654134 (-)
FVB/NJ MGP_FVBNJ_G0016864
protein coding gene Chr10:11396841-11447666 (-)
LP/J MGP_LPJ_G0016944
protein coding gene Chr10:11985513-12041572 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016894
protein coding gene Chr10:12800576-12862212 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017464
protein coding gene Chr10:11843718-11899083 (-)
PWK/PhJ MGP_PWKPhJ_G0016156
protein coding gene Chr10:11429263-11482403 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015939
protein coding gene Chr10:11975983-12024091 (-)
WSB/EiJ MGP_WSBEiJ_G0016433
protein coding gene Chr10:11887387-11952743 (-)



Homology
more
  • Human Ortholog
    VTA1, vesicle trafficking 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VTA1, vesicle trafficking 1
  • Synonyms
    6orf55, C6orf55, DRG-1, DRG1, HSPC228, LIP5, My012, SBP1
  • Links
    NCBI Gene ID: 51534
    neXtProt AC: NX_Q9NP79
    UniProt: Q9NP79

  • Chr Location
    6q24.1-q24.2; chr6:142147162-142224685 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66201 NCBI Gene Model | MGI Sequence Detail 50157 C57BL/6J ±  kb
transcript NM_001429340 RefSeq | MGI Sequence Detail 1468 C57BL/6  
polypeptide Q9CR26 UniProt | EBI | MGI Sequence Detail 309 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000017356 vacuolar protein sorting-associated protein VTA1
  • InterPro Domains
    IPR044538 Vacuolar protein sorting-associated protein Vta1-like
    IPR039431 Vta1/callose synthase, N-terminal
    IPR023175 Vta1/Callose synthase, N-terminal domain superfamily
    IPR041212 Vta1, C-terminal
Molecular
Reagents
less
  • All nucleic 82
    cDNA 82

    Microarray probesets 4
Other
Accession IDs
less
MGI:1915812, MGI:2143754, MGI:2143940
References
more
  • Summaries
    All 31
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 2
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:339600 Hermosilla Aguayo V, et al., ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory