Rpl14 MGI Mouse Gene Detail - MGI:1914365

Symbol

Rpl14
Name

ribosomal protein L14
Synonyms

3100001N19Rik, CAG-ISL-7, CTG-B33, L14

Feature Type

protein coding gene
IDs

MGI:1914365
NCBI Gene: 67115
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr9:120400579-120403724 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 71.74 cM
Mapping Data

2 experiments

SNPs within 2kb

221 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914365	protein coding gene	Chr9:120400510-120403724 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0035437	protein coding gene	Chr9:123435181-123439592 (+)
A/J	MGP_AJ_G0035418	protein coding gene	Chr9:118790817-118793954 (+)
AKR/J	MGP_AKRJ_G0035351	protein coding gene	Chr9:121910279-121916604 (+)
BALB/cJ	MGP_BALBcJ_G0035414	protein coding gene	Chr9:118690820-118693957 (+)
C3H/HeJ	MGP_C3HHeJ_G0035122	protein coding gene	Chr9:122385276-122388413 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0035937	protein coding gene	Chr9:126795553-126798689 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0032819	protein coding gene	Chr9:115980002-115983521 (+)
CAST/EiJ	MGP_CASTEiJ_G0034426	protein coding gene	Chr9:122424366-122427501 (+)
CBA/J	MGP_CBAJ_G0035089	protein coding gene	Chr9:131491788-131498814 (+)
DBA/2J	MGP_DBA2J_G0035248	protein coding gene	Chr9:118248251-118251386 (+)
FVB/NJ	MGP_FVBNJ_G0035195	protein coding gene	Chr9:117136896-117140374 (+)
LP/J	MGP_LPJ_G0035327	protein coding gene	Chr9:123777192-123780593 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0035236	protein coding gene	Chr9:132467880-132471016 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0035956	protein coding gene	Chr9:122329328-122333046 (+)
PWK/PhJ	MGP_PWKPhJ_G0034131	protein coding gene	Chr9:118692011-118695369 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0033967	protein coding gene	Chr9:122405844-122408973 (+)
WSB/EiJ	MGP_WSBEiJ_G0034546	protein coding gene	Chr9:122203712-122208355 (+)

Human Ortholog

RPL14, ribosomal protein L14

Vertebrate Orthologs

5

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RPL14, ribosomal protein L14
Synonyms

CAG-ISL-7, CTG-B33, eL14, hRL14, L14, RL14
Links

HGNC:10305

NCBI Gene ID: 9045

neXtProt AC: NX_P50914

UniProt: P50914
Chr Location

3p22.1; chr3:40457292-40468587 (+) GRCh38

MGI Vertebrate Homology

Rpl14 stringent orthology
1 human;1 mouse;3 rat;1 zebrafish
HCOP

vertebrate homology predictions: RPL14
Gene Tree

Rpl14

Diseases

1 with human RPL14 associations

				Human Disease	Mouse Models
				systemic lupus erythematosus IDs systemic lupus erythematosus DOID:9074 ICD10CM:M32.9 ICD9CM:710.0 KEGG:05322 MESH:D008180 NCI:C3201 OMIM:152700 OMIM:300809 OMIM:605480 OMIM:608437 OMIM:609903 OMIM:609939 OMIM:610065 OMIM:610066 OMIM:612254 OMIM:612378 OMIM:613145 OMIM:614420 ORDO:536 UMLS_CUI:C0024141

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

2 phenotype references

All Mutations and Alleles

3
Gene trapped

3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

6 strains or lines available

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All GO Annotations

27
GO References

8

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

734
Tissues

24
cDNA Data

13
Literature Summary

8

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rpl14

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All Sequences

53
RefSeq

2
UniProt

3
CCDS

CCDS40809.1

Ensembl

ENSMUSG00000025794 (Evidence)
NCBI Gene

67115

			Length	Strain/Species	Flank
genomic	67115	NCBI Gene Model \| MGI Sequence Detail	3146	C57BL/6J	± kb
transcript	NM_025974	RefSeq \| MGI Sequence Detail	944	C57BL/6
polypeptide	Q9CR57	UniProt \| EBI \| MGI Sequence Detail	217	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000014194 large ribosomal subunit protein eL14

(term hierarchy)
PDB

6SWA, 7CPU, 7CPV, 7LS1, 7LS2
InterPro Domains

IPR039660 Large ribosomal subunit protein eL14

IPR002784 Large ribosomal subunit protein eL14 domain

IPR041985 Large ribosomal subunit protein eL14, KOW motif

IPR014722 Large ribosomal subunit protein uL2, domain 2

IPR008991 Translation protein SH3-like domain superfamily
GlyGen

Q9CR57 1 site, 1 O-linked glycan (1 site)

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All nucleic 16

cDNA 16

Microarray probesets 8

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MGI:2141807, MGI:2142088

Summaries

All 39

Developmental Gene Expression 8

Gene Ontology 8

Phenotypes 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:336923 Jiang X, et al., Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice. Nat Commun. 2023 Jun 22;14(1):3729

TSS for Rpl14:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr87749	Chr9:120400542-120400553 (+)	-31 bp
Tssr87750	Chr9:120400564-120400588 (+)	-3 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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