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Lrrc40 Gene Detail
Summary
  • Symbol
    Lrrc40
  • Name
    leucine rich repeat containing 40
  • Synonyms
    2610040E16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914394
    NCBI Gene: 67144
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:157742340-157772727 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 81.65 cM, cytoband H4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    588 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914394
 protein coding gene Chr3:157742299-157774124 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028016
 protein coding gene Chr3:162194864-162226470 (+)
A/J MGP_AJ_G0027974
 protein coding gene Chr3:156284663-156316639 (+)
AKR/J MGP_AKRJ_G0027940
 protein coding gene Chr3:160434669-160466403 (+)
BALB/cJ MGP_BALBcJ_G0027986
 protein coding gene Chr3:156098029-156129804 (+)
C3H/HeJ MGP_C3HHeJ_G0027716
 protein coding gene Chr3:160833673-160866115 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028429
 protein coding gene Chr3:167511615-167543748 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0025768
 protein coding gene Chr3:150894635-150926530 (+)
CAST/EiJ MGP_CASTEiJ_G0027169
 protein coding gene Chr3:160979912-161014989 (+)
CBA/J MGP_CBAJ_G0027691
 protein coding gene Chr3:173458108-173491588 (+)
DBA/2J MGP_DBA2J_G0027831
 protein coding gene Chr3:155332438-155365030 (+)
FVB/NJ MGP_FVBNJ_G0027798
 protein coding gene Chr3:152682834-152714692 (+)
LP/J MGP_LPJ_G0027942
 protein coding gene Chr3:163525708-163557443 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0027831
 protein coding gene Chr3:182043202-182075580 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028488
 protein coding gene Chr3:160113233-160147511 (+)
PWK/PhJ MGP_PWKPhJ_G0026892
 protein coding gene Chr3:155261518-155293846 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026720
 protein coding gene Chr3:158327457-158359317 (+)
WSB/EiJ MGP_WSBEiJ_G0027249
 protein coding gene Chr3:161077520-161110935 (+)



Homology
more
  • Human Ortholog
    LRRC40, leucine rich repeat containing 40
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC40, leucine rich repeat containing 40
  • Synonyms
    dJ677H15.1
  • Links
    NCBI Gene ID: 55631
    neXtProt AC: NX_Q9H9A6
    UniProt: Q9H9A6

  • Chr Location
    1p31.1; chr1:70144805-70205579 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    19
  • cDNA Data
    12
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67144 NCBI Gene Model | MGI Sequence Detail 30388 C57BL/6J ±  kb
transcript NM_001426731 RefSeq | MGI Sequence Detail 2775 C57BL/6  
polypeptide Q9CRC8 UniProt | EBI | MGI Sequence Detail 602 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    8 Sequences
  • Protein Ontology
    PR:000029599 leucine-rich repeat-containing protein 40
    (term hierarchy)
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR050216 Leucine-rich repeat domain-containing protein
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003591 Leucine-rich repeat, typical subtype
  • GlyGen
    Q9CRC8 3 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 5
Other
Accession IDs
less
MGI:2139803
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory